STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
recCExodeoxyribonuclease V, gamma subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and r [...] (1238 aa)    
Predicted Functional Partners:
recD
Exodeoxyribonuclease V, alpha subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and r [...]
 
 0.998
recB
Exodeoxyribonuclease V, beta subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and re [...]
 
 
 0.998
HELO_3297
Hypothetical protein; T-DNA border endonuclease virD2 - Agrobacterium rhizogenes, High confidence in function and specificity.
  
 
 0.756
HELO_3298
Putative DNA relaxase/nickase, TraS/VirD2-like; T-DNA border endonuclease virD2 - Agrobacterium tumefaciens (strain C58 / ATCC 33970), High confidence in function and specificity.
  
 
 0.756
traA
TraI.
  
 
 0.604
HELO_1489
Transcriptional regulator, LysR family; Uncharacterized HTH-type transcriptional regulator yhjC - Escherichia coli (strain K12),InterPro: LysR substrate binding domain, Specificity unclear; Belongs to the LysR transcriptional regulatory family.
       0.556
HELO_1507
Transcriptional regulator, AraC family; Putative regulatory protein ada - Mycobacterium tuberculosis,InterPro: HhH-GPD, High confidence in function and specificity.
     
 0.445
HELO_2378
Hypothetical protein; HTH-type transcriptional regulator sgrR -Photorhabdus luminescens subsp. laumondii,InterPro: TatD-related deoxyribonuclease, Hypothetical protein.
  
     0.411
HELO_2376
Hypothetical protein; Laminin subunit alpha-3 precursor - Mus musculus (Mouse), Specificity unclear.
  
     0.406
HELO_2377
Hypothetical protein; DNA-directed RNA polymerase subunit beta - Aquifex pyrophilus, Hypothetical protein.
  
     0.400
Your Current Organism:
Halomonas elongata
NCBI taxonomy Id: 768066
Other names: H. elongata DSM 2581, Halomonas elongata ATCC 33173, Halomonas elongata DSM 2581, Halomonas elongata str. DSM 2581, Halomonas elongata strain DSM 2581
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.