STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hyiHydroxypyruvate isomerase - Escherichia coli (strain K12),InterPro: AP endonuclease family 2, High confidence in function and specificity; Belongs to the hyi family. (258 aa)    
Predicted Functional Partners:
gcl
Glyoxylate carboligase - Escherichia coli O157:H7,InterPro: Glyoxylate carboligase, High confidence in function and specificity; Belongs to the TPP enzyme family.
 
 
 0.991
glxR
2-hydroxy-3-oxopropionate reductase; High confidence in function and specificity.
 
 0.978
mmsB
2-hydroxy-3-oxopropionate reductase; Nuclear protein NP60 - Gallus gallus (Chicken),InterPro: 6-phosphogluconate dehydrogenase NAD binding domain, High confidence in function and specificity.
 
 0.934
HELO_4234
Hypothetical protein; Putative hydroxypyruvate isomerase - Mus musculus (Mouse),InterPro: AP endonuclease family 2, High confidence in function and specificity; Belongs to the hyi family.
  
  
 
0.926
HELO_1208
Xylose isomerase domain protein TIM barrel; Putative hydroxypyruvate isomerase - Xenopus laevis (African clawed frog),InterPro: Twin-arginine translocation pathway signal, Specificity unclear; Belongs to the hyi family.
  
  
 
0.924
ghrA
Erythronate-4-phosphate dehydrogenase - Shewanella baltica (strain OS185),InterPro: D-isomer specific 2-hydroxyacid dehydrogenase NAD binding domain, High confidence in function and specificity.
  
 
  0.922
hprA
Glycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
   
 
 0.903
ttuD
Hydroxypyruvate reductase; Glycerate kinase - Homo sapiens (Human),InterPro: MOFRL, High confidence in function and specificity.
 
   
 0.701
Your Current Organism:
Halomonas elongata
NCBI taxonomy Id: 768066
Other names: H. elongata DSM 2581, Halomonas elongata ATCC 33173, Halomonas elongata DSM 2581, Halomonas elongata str. DSM 2581, Halomonas elongata strain DSM 2581
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