| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| HELO_1208 | HELO_4234 | HELO_1208 | HELO_4234 | Xylose isomerase domain protein TIM barrel; Putative hydroxypyruvate isomerase - Xenopus laevis (African clawed frog),InterPro: Twin-arginine translocation pathway signal, Specificity unclear; Belongs to the hyi family. | Hypothetical protein; Putative hydroxypyruvate isomerase - Mus musculus (Mouse),InterPro: AP endonuclease family 2, High confidence in function and specificity; Belongs to the hyi family. | 0.925 |
| HELO_1208 | gcl | HELO_1208 | HELO_1601 | Xylose isomerase domain protein TIM barrel; Putative hydroxypyruvate isomerase - Xenopus laevis (African clawed frog),InterPro: Twin-arginine translocation pathway signal, Specificity unclear; Belongs to the hyi family. | Glyoxylate carboligase - Escherichia coli O157:H7,InterPro: Glyoxylate carboligase, High confidence in function and specificity; Belongs to the TPP enzyme family. | 0.919 |
| HELO_1208 | ghrA | HELO_1208 | HELO_3667 | Xylose isomerase domain protein TIM barrel; Putative hydroxypyruvate isomerase - Xenopus laevis (African clawed frog),InterPro: Twin-arginine translocation pathway signal, Specificity unclear; Belongs to the hyi family. | Erythronate-4-phosphate dehydrogenase - Shewanella baltica (strain OS185),InterPro: D-isomer specific 2-hydroxyacid dehydrogenase NAD binding domain, High confidence in function and specificity. | 0.915 |
| HELO_1208 | glxR | HELO_1208 | HELO_1603 | Xylose isomerase domain protein TIM barrel; Putative hydroxypyruvate isomerase - Xenopus laevis (African clawed frog),InterPro: Twin-arginine translocation pathway signal, Specificity unclear; Belongs to the hyi family. | 2-hydroxy-3-oxopropionate reductase; High confidence in function and specificity. | 0.911 |
| HELO_1208 | hprA | HELO_1208 | HELO_2556 | Xylose isomerase domain protein TIM barrel; Putative hydroxypyruvate isomerase - Xenopus laevis (African clawed frog),InterPro: Twin-arginine translocation pathway signal, Specificity unclear; Belongs to the hyi family. | Glycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.903 |
| HELO_1208 | hyi | HELO_1208 | HELO_1602 | Xylose isomerase domain protein TIM barrel; Putative hydroxypyruvate isomerase - Xenopus laevis (African clawed frog),InterPro: Twin-arginine translocation pathway signal, Specificity unclear; Belongs to the hyi family. | Hydroxypyruvate isomerase - Escherichia coli (strain K12),InterPro: AP endonuclease family 2, High confidence in function and specificity; Belongs to the hyi family. | 0.924 |
| HELO_1208 | mmsB | HELO_1208 | HELO_1047 | Xylose isomerase domain protein TIM barrel; Putative hydroxypyruvate isomerase - Xenopus laevis (African clawed frog),InterPro: Twin-arginine translocation pathway signal, Specificity unclear; Belongs to the hyi family. | 2-hydroxy-3-oxopropionate reductase; Nuclear protein NP60 - Gallus gallus (Chicken),InterPro: 6-phosphogluconate dehydrogenase NAD binding domain, High confidence in function and specificity. | 0.911 |
| HELO_4234 | HELO_1208 | HELO_4234 | HELO_1208 | Hypothetical protein; Putative hydroxypyruvate isomerase - Mus musculus (Mouse),InterPro: AP endonuclease family 2, High confidence in function and specificity; Belongs to the hyi family. | Xylose isomerase domain protein TIM barrel; Putative hydroxypyruvate isomerase - Xenopus laevis (African clawed frog),InterPro: Twin-arginine translocation pathway signal, Specificity unclear; Belongs to the hyi family. | 0.925 |
| HELO_4234 | gcl | HELO_4234 | HELO_1601 | Hypothetical protein; Putative hydroxypyruvate isomerase - Mus musculus (Mouse),InterPro: AP endonuclease family 2, High confidence in function and specificity; Belongs to the hyi family. | Glyoxylate carboligase - Escherichia coli O157:H7,InterPro: Glyoxylate carboligase, High confidence in function and specificity; Belongs to the TPP enzyme family. | 0.919 |
| HELO_4234 | ghrA | HELO_4234 | HELO_3667 | Hypothetical protein; Putative hydroxypyruvate isomerase - Mus musculus (Mouse),InterPro: AP endonuclease family 2, High confidence in function and specificity; Belongs to the hyi family. | Erythronate-4-phosphate dehydrogenase - Shewanella baltica (strain OS185),InterPro: D-isomer specific 2-hydroxyacid dehydrogenase NAD binding domain, High confidence in function and specificity. | 0.903 |
| HELO_4234 | glxR | HELO_4234 | HELO_1603 | Hypothetical protein; Putative hydroxypyruvate isomerase - Mus musculus (Mouse),InterPro: AP endonuclease family 2, High confidence in function and specificity; Belongs to the hyi family. | 2-hydroxy-3-oxopropionate reductase; High confidence in function and specificity. | 0.909 |
| HELO_4234 | hprA | HELO_4234 | HELO_2556 | Hypothetical protein; Putative hydroxypyruvate isomerase - Mus musculus (Mouse),InterPro: AP endonuclease family 2, High confidence in function and specificity; Belongs to the hyi family. | Glycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.903 |
| HELO_4234 | hyi | HELO_4234 | HELO_1602 | Hypothetical protein; Putative hydroxypyruvate isomerase - Mus musculus (Mouse),InterPro: AP endonuclease family 2, High confidence in function and specificity; Belongs to the hyi family. | Hydroxypyruvate isomerase - Escherichia coli (strain K12),InterPro: AP endonuclease family 2, High confidence in function and specificity; Belongs to the hyi family. | 0.926 |
| HELO_4234 | mmsB | HELO_4234 | HELO_1047 | Hypothetical protein; Putative hydroxypyruvate isomerase - Mus musculus (Mouse),InterPro: AP endonuclease family 2, High confidence in function and specificity; Belongs to the hyi family. | 2-hydroxy-3-oxopropionate reductase; Nuclear protein NP60 - Gallus gallus (Chicken),InterPro: 6-phosphogluconate dehydrogenase NAD binding domain, High confidence in function and specificity. | 0.909 |
| gcl | HELO_1208 | HELO_1601 | HELO_1208 | Glyoxylate carboligase - Escherichia coli O157:H7,InterPro: Glyoxylate carboligase, High confidence in function and specificity; Belongs to the TPP enzyme family. | Xylose isomerase domain protein TIM barrel; Putative hydroxypyruvate isomerase - Xenopus laevis (African clawed frog),InterPro: Twin-arginine translocation pathway signal, Specificity unclear; Belongs to the hyi family. | 0.919 |
| gcl | HELO_4234 | HELO_1601 | HELO_4234 | Glyoxylate carboligase - Escherichia coli O157:H7,InterPro: Glyoxylate carboligase, High confidence in function and specificity; Belongs to the TPP enzyme family. | Hypothetical protein; Putative hydroxypyruvate isomerase - Mus musculus (Mouse),InterPro: AP endonuclease family 2, High confidence in function and specificity; Belongs to the hyi family. | 0.919 |
| gcl | ghrA | HELO_1601 | HELO_3667 | Glyoxylate carboligase - Escherichia coli O157:H7,InterPro: Glyoxylate carboligase, High confidence in function and specificity; Belongs to the TPP enzyme family. | Erythronate-4-phosphate dehydrogenase - Shewanella baltica (strain OS185),InterPro: D-isomer specific 2-hydroxyacid dehydrogenase NAD binding domain, High confidence in function and specificity. | 0.900 |
| gcl | glxR | HELO_1601 | HELO_1603 | Glyoxylate carboligase - Escherichia coli O157:H7,InterPro: Glyoxylate carboligase, High confidence in function and specificity; Belongs to the TPP enzyme family. | 2-hydroxy-3-oxopropionate reductase; High confidence in function and specificity. | 0.979 |
| gcl | hprA | HELO_1601 | HELO_2556 | Glyoxylate carboligase - Escherichia coli O157:H7,InterPro: Glyoxylate carboligase, High confidence in function and specificity; Belongs to the TPP enzyme family. | Glycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.900 |
| gcl | hyi | HELO_1601 | HELO_1602 | Glyoxylate carboligase - Escherichia coli O157:H7,InterPro: Glyoxylate carboligase, High confidence in function and specificity; Belongs to the TPP enzyme family. | Hydroxypyruvate isomerase - Escherichia coli (strain K12),InterPro: AP endonuclease family 2, High confidence in function and specificity; Belongs to the hyi family. | 0.991 |