| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| HELO_1757 | fadB | HELO_1757 | HELO_1758 | Hypothetical protein; Filamin-A - Mus musculus (Mouse), Hypothetical protein. | Multifunctional fatty acid oxidation complex subunit alpha; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. | 0.795 |
| HELO_1757 | slyA | HELO_1757 | HELO_1756 | Hypothetical protein; Filamin-A - Mus musculus (Mouse), Hypothetical protein. | Transcriptional regulator slyA - Sodalis glossinidius (strain morsitans),InterPro: Bacterial regulatory protein MarR family, High confidence in function and specificity. | 0.783 |
| HELO_3559 | birA | HELO_3559 | HELO_1221 | Probable two-component sensor; Phytochrome 1 - Selaginella martensii (Martenss spike moss),InterPro: Na+/solute symporter, Specificity unclear. | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.582 |
| HELO_3559 | fadB | HELO_3559 | HELO_1758 | Probable two-component sensor; Phytochrome 1 - Selaginella martensii (Martenss spike moss),InterPro: Na+/solute symporter, Specificity unclear. | Multifunctional fatty acid oxidation complex subunit alpha; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. | 0.889 |
| HELO_3559 | slyA | HELO_3559 | HELO_1756 | Probable two-component sensor; Phytochrome 1 - Selaginella martensii (Martenss spike moss),InterPro: Na+/solute symporter, Specificity unclear. | Transcriptional regulator slyA - Sodalis glossinidius (strain morsitans),InterPro: Bacterial regulatory protein MarR family, High confidence in function and specificity. | 0.422 |
| birA | HELO_3559 | HELO_1221 | HELO_3559 | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Probable two-component sensor; Phytochrome 1 - Selaginella martensii (Martenss spike moss),InterPro: Na+/solute symporter, Specificity unclear. | 0.582 |
| birA | slyA | HELO_1221 | HELO_1756 | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Transcriptional regulator slyA - Sodalis glossinidius (strain morsitans),InterPro: Bacterial regulatory protein MarR family, High confidence in function and specificity. | 0.426 |
| fadB | HELO_1757 | HELO_1758 | HELO_1757 | Multifunctional fatty acid oxidation complex subunit alpha; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. | Hypothetical protein; Filamin-A - Mus musculus (Mouse), Hypothetical protein. | 0.795 |
| fadB | HELO_3559 | HELO_1758 | HELO_3559 | Multifunctional fatty acid oxidation complex subunit alpha; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. | Probable two-component sensor; Phytochrome 1 - Selaginella martensii (Martenss spike moss),InterPro: Na+/solute symporter, Specificity unclear. | 0.889 |
| fadB | slyA | HELO_1758 | HELO_1756 | Multifunctional fatty acid oxidation complex subunit alpha; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. | Transcriptional regulator slyA - Sodalis glossinidius (strain morsitans),InterPro: Bacterial regulatory protein MarR family, High confidence in function and specificity. | 0.456 |
| slyA | HELO_1757 | HELO_1756 | HELO_1757 | Transcriptional regulator slyA - Sodalis glossinidius (strain morsitans),InterPro: Bacterial regulatory protein MarR family, High confidence in function and specificity. | Hypothetical protein; Filamin-A - Mus musculus (Mouse), Hypothetical protein. | 0.783 |
| slyA | HELO_3559 | HELO_1756 | HELO_3559 | Transcriptional regulator slyA - Sodalis glossinidius (strain morsitans),InterPro: Bacterial regulatory protein MarR family, High confidence in function and specificity. | Probable two-component sensor; Phytochrome 1 - Selaginella martensii (Martenss spike moss),InterPro: Na+/solute symporter, Specificity unclear. | 0.422 |
| slyA | birA | HELO_1756 | HELO_1221 | Transcriptional regulator slyA - Sodalis glossinidius (strain morsitans),InterPro: Bacterial regulatory protein MarR family, High confidence in function and specificity. | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.426 |
| slyA | fadB | HELO_1756 | HELO_1758 | Transcriptional regulator slyA - Sodalis glossinidius (strain morsitans),InterPro: Bacterial regulatory protein MarR family, High confidence in function and specificity. | Multifunctional fatty acid oxidation complex subunit alpha; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. | 0.456 |