| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| HELO_1294 | HELO_2768 | HELO_1294 | HELO_2768 | Retinal dehydrogenase 1 - Homo sapiens (Human),InterPro: Aldehyde dehydrogenase, Specificity unclear; Belongs to the aldehyde dehydrogenase family. | Aldehyde dehydrogenase mitochondrial precursor -Pongo pygmaeus (Bornean orangutan),InterPro: Aldehyde dehydrogenase, Specificity unclear. | 0.902 |
| HELO_1294 | HELO_3241 | HELO_1294 | HELO_3241 | Retinal dehydrogenase 1 - Homo sapiens (Human),InterPro: Aldehyde dehydrogenase, Specificity unclear; Belongs to the aldehyde dehydrogenase family. | Glucose-methanol-choline oxidoreductase; Choline dehydrogenase - Serratia proteamaculans (strain 568),InterPro: Glucose-methanol-choline oxidoreductase, Specificity unclear. | 0.960 |
| HELO_1294 | betA | HELO_1294 | HELO_1859 | Retinal dehydrogenase 1 - Homo sapiens (Human),InterPro: Aldehyde dehydrogenase, Specificity unclear; Belongs to the aldehyde dehydrogenase family. | Choline dehydrogenase BetA; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | 0.954 |
| HELO_1294 | betB | HELO_1294 | HELO_1860 | Retinal dehydrogenase 1 - Homo sapiens (Human),InterPro: Aldehyde dehydrogenase, Specificity unclear; Belongs to the aldehyde dehydrogenase family. | Betaine aldehyde dehydrogenase BetB; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | 0.911 |
| HELO_1294 | fmt | HELO_1294 | HELO_1375 | Retinal dehydrogenase 1 - Homo sapiens (Human),InterPro: Aldehyde dehydrogenase, Specificity unclear; Belongs to the aldehyde dehydrogenase family. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.432 |
| HELO_1862 | betA | HELO_1862 | HELO_1859 | ABC-type transport system periplasmic substrate-binding protein. | Choline dehydrogenase BetA; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | 0.738 |
| HELO_1862 | betB | HELO_1862 | HELO_1860 | ABC-type transport system periplasmic substrate-binding protein. | Betaine aldehyde dehydrogenase BetB; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | 0.782 |
| HELO_1862 | betI | HELO_1862 | HELO_1861 | ABC-type transport system periplasmic substrate-binding protein. | Transcriptional regulator BetI; Repressor involved in choline regulation of the bet genes. | 0.858 |
| HELO_1862 | fadE | HELO_1862 | HELO_1858 | ABC-type transport system periplasmic substrate-binding protein. | Acyl-coenzyme A dehydrogenase - Salmonella typhimurium,InterPro: Acyl-CoA dehydrogenase C-terminal,High confidence in function and specificity. | 0.589 |
| HELO_2768 | HELO_1294 | HELO_2768 | HELO_1294 | Aldehyde dehydrogenase mitochondrial precursor -Pongo pygmaeus (Bornean orangutan),InterPro: Aldehyde dehydrogenase, Specificity unclear. | Retinal dehydrogenase 1 - Homo sapiens (Human),InterPro: Aldehyde dehydrogenase, Specificity unclear; Belongs to the aldehyde dehydrogenase family. | 0.902 |
| HELO_2768 | HELO_3241 | HELO_2768 | HELO_3241 | Aldehyde dehydrogenase mitochondrial precursor -Pongo pygmaeus (Bornean orangutan),InterPro: Aldehyde dehydrogenase, Specificity unclear. | Glucose-methanol-choline oxidoreductase; Choline dehydrogenase - Serratia proteamaculans (strain 568),InterPro: Glucose-methanol-choline oxidoreductase, Specificity unclear. | 0.960 |
| HELO_2768 | betA | HELO_2768 | HELO_1859 | Aldehyde dehydrogenase mitochondrial precursor -Pongo pygmaeus (Bornean orangutan),InterPro: Aldehyde dehydrogenase, Specificity unclear. | Choline dehydrogenase BetA; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | 0.954 |
| HELO_2768 | betB | HELO_2768 | HELO_1860 | Aldehyde dehydrogenase mitochondrial precursor -Pongo pygmaeus (Bornean orangutan),InterPro: Aldehyde dehydrogenase, Specificity unclear. | Betaine aldehyde dehydrogenase BetB; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | 0.913 |
| HELO_3241 | HELO_1294 | HELO_3241 | HELO_1294 | Glucose-methanol-choline oxidoreductase; Choline dehydrogenase - Serratia proteamaculans (strain 568),InterPro: Glucose-methanol-choline oxidoreductase, Specificity unclear. | Retinal dehydrogenase 1 - Homo sapiens (Human),InterPro: Aldehyde dehydrogenase, Specificity unclear; Belongs to the aldehyde dehydrogenase family. | 0.960 |
| HELO_3241 | HELO_2768 | HELO_3241 | HELO_2768 | Glucose-methanol-choline oxidoreductase; Choline dehydrogenase - Serratia proteamaculans (strain 568),InterPro: Glucose-methanol-choline oxidoreductase, Specificity unclear. | Aldehyde dehydrogenase mitochondrial precursor -Pongo pygmaeus (Bornean orangutan),InterPro: Aldehyde dehydrogenase, Specificity unclear. | 0.960 |
| HELO_3241 | betA | HELO_3241 | HELO_1859 | Glucose-methanol-choline oxidoreductase; Choline dehydrogenase - Serratia proteamaculans (strain 568),InterPro: Glucose-methanol-choline oxidoreductase, Specificity unclear. | Choline dehydrogenase BetA; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | 0.913 |
| HELO_3241 | betB | HELO_3241 | HELO_1860 | Glucose-methanol-choline oxidoreductase; Choline dehydrogenase - Serratia proteamaculans (strain 568),InterPro: Glucose-methanol-choline oxidoreductase, Specificity unclear. | Betaine aldehyde dehydrogenase BetB; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | 0.967 |
| HELO_3241 | betI | HELO_3241 | HELO_1861 | Glucose-methanol-choline oxidoreductase; Choline dehydrogenase - Serratia proteamaculans (strain 568),InterPro: Glucose-methanol-choline oxidoreductase, Specificity unclear. | Transcriptional regulator BetI; Repressor involved in choline regulation of the bet genes. | 0.562 |
| betA | HELO_1294 | HELO_1859 | HELO_1294 | Choline dehydrogenase BetA; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | Retinal dehydrogenase 1 - Homo sapiens (Human),InterPro: Aldehyde dehydrogenase, Specificity unclear; Belongs to the aldehyde dehydrogenase family. | 0.954 |
| betA | HELO_1862 | HELO_1859 | HELO_1862 | Choline dehydrogenase BetA; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | ABC-type transport system periplasmic substrate-binding protein. | 0.738 |