STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bioHK02170 biotin biosynthesis protein BioH; Carboxylesterase bioH - Yersinia enterocolitica serotype O:8 / biotype 1B (strain 8081),InterPro: Esterase/lipase/thioesterase, High confidence in function and specificity. (244 aa)    
Predicted Functional Partners:
bioF
8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
  
 0.993
bioC
K02169 biotin synthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.
  
 0.986
wcbT
Putative 8-amino-7-oxononanoate synthase; 5-aminolevulinate synthase mitochondrial precursor -Kluyveromyces lactis (Yeast) (Candida sphaerica),InterPro: Aminotransferase class I and II, High confidence in function and specificity.
  
 0.949
bioD
Dithiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
 
  
 0.935
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
  
  
 0.916
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 
 0.849
HELO_4099
Cytochrome P450; Fatty acid synthase - Bos taurus (Bovine),InterPro: Cytochrome P450, High confidence in function and specificity.
  
 
 0.829
comF
Competence protein F; Protein gntX - Salmonella typhi,InterPro: Bipartite nuclear localization signal, High confidence in function and specificity.
       0.621
HELO_2029
Hypothetical protein predicted by Glimmer/Critica.
  
     0.533
HELO_2847
Protein sirB2 - Escherichia coli (strain K12),InterPro: Invasion gene expression up-regulator SirB,Specificity unclear.
 
     0.483
Your Current Organism:
Halomonas elongata
NCBI taxonomy Id: 768066
Other names: H. elongata DSM 2581, Halomonas elongata ATCC 33173, Halomonas elongata DSM 2581, Halomonas elongata str. DSM 2581, Halomonas elongata strain DSM 2581
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