| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| HELO_2308 | HELO_2309 | HELO_2308 | HELO_2309 | UPF0012 hydrolase yhcX - Bacillus subtilis,InterPro: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase, Specificity unclear. | UPF0192 protein PA4489 precursor - Pseudomonas aeruginosa, Hypothetical protein. | 0.957 |
| HELO_2308 | benE | HELO_2308 | HELO_2310 | UPF0012 hydrolase yhcX - Bacillus subtilis,InterPro: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase, Specificity unclear. | Benzoate membrane transport protein - Acinetobacter sp. (strain ADP1),InterPro: Benzoate membrane transport protein, High confidence in function and specificity. | 0.538 |
| HELO_2308 | proS | HELO_2308 | HELO_2307 | UPF0012 hydrolase yhcX - Bacillus subtilis,InterPro: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase, Specificity unclear. | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] | 0.531 |
| HELO_2308 | purL | HELO_2308 | HELO_1672 | UPF0012 hydrolase yhcX - Bacillus subtilis,InterPro: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase, Specificity unclear. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.426 |
| HELO_2309 | HELO_2308 | HELO_2309 | HELO_2308 | UPF0192 protein PA4489 precursor - Pseudomonas aeruginosa, Hypothetical protein. | UPF0012 hydrolase yhcX - Bacillus subtilis,InterPro: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase, Specificity unclear. | 0.957 |
| HELO_2309 | benE | HELO_2309 | HELO_2310 | UPF0192 protein PA4489 precursor - Pseudomonas aeruginosa, Hypothetical protein. | Benzoate membrane transport protein - Acinetobacter sp. (strain ADP1),InterPro: Benzoate membrane transport protein, High confidence in function and specificity. | 0.538 |
| HELO_2309 | proS | HELO_2309 | HELO_2307 | UPF0192 protein PA4489 precursor - Pseudomonas aeruginosa, Hypothetical protein. | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] | 0.519 |
| benE | HELO_2308 | HELO_2310 | HELO_2308 | Benzoate membrane transport protein - Acinetobacter sp. (strain ADP1),InterPro: Benzoate membrane transport protein, High confidence in function and specificity. | UPF0012 hydrolase yhcX - Bacillus subtilis,InterPro: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase, Specificity unclear. | 0.538 |
| benE | HELO_2309 | HELO_2310 | HELO_2309 | Benzoate membrane transport protein - Acinetobacter sp. (strain ADP1),InterPro: Benzoate membrane transport protein, High confidence in function and specificity. | UPF0192 protein PA4489 precursor - Pseudomonas aeruginosa, Hypothetical protein. | 0.538 |
| proS | HELO_2308 | HELO_2307 | HELO_2308 | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] | UPF0012 hydrolase yhcX - Bacillus subtilis,InterPro: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase, Specificity unclear. | 0.531 |
| proS | HELO_2309 | HELO_2307 | HELO_2309 | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] | UPF0192 protein PA4489 precursor - Pseudomonas aeruginosa, Hypothetical protein. | 0.519 |
| proS | purL | HELO_2307 | HELO_1672 | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.540 |
| purL | HELO_2308 | HELO_1672 | HELO_2308 | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | UPF0012 hydrolase yhcX - Bacillus subtilis,InterPro: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase, Specificity unclear. | 0.426 |
| purL | proS | HELO_1672 | HELO_2307 | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] | 0.540 |