STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HELO_2381Allophanate hydrolase subunit 2; Uncharacterized protein ybgK - Escherichia coli (strain K12),InterPro: Urea amidolyase-related, Specificity unclear. (312 aa)    
Predicted Functional Partners:
pxpA
K07160; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
 
 0.999
HELO_2380
Allophanate hydrolase subunit 1; Kinase A inhibitor - Bacillus subtilis,InterPro: Protein of unknown function DUF213, Specificity unclear.
 
 0.999
accA
Methylcrotonoyl-CoA carboxylase, biotin carboxylase subunit.
 
  
 0.917
accC
acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
      0.905
gshA
Glutamate--cysteine ligase - Enterobacter sakazakii (strain ATCC BAA-894),InterPro: Glutamate--cysteine ligase,High confidence in function and specificity; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
     
  0.900
HELO_2027
Gamma-glutamyltranspeptidase; Specificity unclear.
     
  0.900
chaC
K07232 cation transport protein ChaC; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.
     
  0.900
ggt
Gamma-glutamyltransferase; Gamma-glutamyltranspeptidase precursor - Escherichia coli (strain K12),InterPro: Bipartite nuclear localization signal, High confidence in function and specificity.
     
  0.900
gltB
Glutamate synthase (NADPH), large subunit; Catalyzes the conversion of L-glutamine and 2-oxoglutarate into two molecules of L-glutamate.
   
 
  0.818
putA
Bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
   
 
  0.817
Your Current Organism:
Halomonas elongata
NCBI taxonomy Id: 768066
Other names: H. elongata DSM 2581, Halomonas elongata ATCC 33173, Halomonas elongata DSM 2581, Halomonas elongata str. DSM 2581, Halomonas elongata strain DSM 2581
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