| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| HELO_3530 | HELO_3532 | HELO_3530 | HELO_3532 | Transcriptional regulator, AsnC family; Uncharacterized HTH-type transcriptional regulator PH1519 - Pyrococcus horikoshii, Specificity unclear. | K09786 hypothetical protein; UPF0229 protein Csal_0882 - Chromohalobacter salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB 13768),InterPro: Protein of unknown function DUF444, High confidence in function and specificity; Belongs to the UPF0229 family. | 0.505 |
| HELO_3530 | nucA | HELO_3530 | HELO_3529 | Transcriptional regulator, AsnC family; Uncharacterized HTH-type transcriptional regulator PH1519 - Pyrococcus horikoshii, Specificity unclear. | DNA/RNA non-specific endonuclease; High confidence in function and specificity. | 0.803 |
| HELO_3530 | ycgB | HELO_3530 | HELO_3531 | Transcriptional regulator, AsnC family; Uncharacterized HTH-type transcriptional regulator PH1519 - Pyrococcus horikoshii, Specificity unclear. | Uncharacterized protein ycgB - Escherichia coli (strain K12),InterPro: SpoVR, High confidence in function and specificity. | 0.549 |
| HELO_3532 | HELO_3530 | HELO_3532 | HELO_3530 | K09786 hypothetical protein; UPF0229 protein Csal_0882 - Chromohalobacter salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB 13768),InterPro: Protein of unknown function DUF444, High confidence in function and specificity; Belongs to the UPF0229 family. | Transcriptional regulator, AsnC family; Uncharacterized HTH-type transcriptional regulator PH1519 - Pyrococcus horikoshii, Specificity unclear. | 0.505 |
| HELO_3532 | nucA | HELO_3532 | HELO_3529 | K09786 hypothetical protein; UPF0229 protein Csal_0882 - Chromohalobacter salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB 13768),InterPro: Protein of unknown function DUF444, High confidence in function and specificity; Belongs to the UPF0229 family. | DNA/RNA non-specific endonuclease; High confidence in function and specificity. | 0.408 |
| HELO_3532 | ycgB | HELO_3532 | HELO_3531 | K09786 hypothetical protein; UPF0229 protein Csal_0882 - Chromohalobacter salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB 13768),InterPro: Protein of unknown function DUF444, High confidence in function and specificity; Belongs to the UPF0229 family. | Uncharacterized protein ycgB - Escherichia coli (strain K12),InterPro: SpoVR, High confidence in function and specificity. | 0.996 |
| HELO_3630 | HELO_3931 | HELO_3630 | HELO_3931 | Epimerase; High confidence in function and specificity. | Beta-lactamase-like; Ribonuclease Z - Bacillus cereus (strain ATCC 10987),InterPro: Beta-lactamase-like, High confidence in function and specificity. | 0.432 |
| HELO_3630 | nucA | HELO_3630 | HELO_3529 | Epimerase; High confidence in function and specificity. | DNA/RNA non-specific endonuclease; High confidence in function and specificity. | 0.666 |
| HELO_3931 | HELO_3630 | HELO_3931 | HELO_3630 | Beta-lactamase-like; Ribonuclease Z - Bacillus cereus (strain ATCC 10987),InterPro: Beta-lactamase-like, High confidence in function and specificity. | Epimerase; High confidence in function and specificity. | 0.432 |
| HELO_3931 | nucA | HELO_3931 | HELO_3529 | Beta-lactamase-like; Ribonuclease Z - Bacillus cereus (strain ATCC 10987),InterPro: Beta-lactamase-like, High confidence in function and specificity. | DNA/RNA non-specific endonuclease; High confidence in function and specificity. | 0.886 |
| fdsB | nucA | HELO_1898 | HELO_3529 | NADH dehydrogenase (quinone); NADH-quinone oxidoreductase subunit F - Rickettsia bellii (strain OSU 85-389),InterPro: Respiratory-chain NADH dehydrogenase 51 kDa subunit, High confidence in function and specificity. | DNA/RNA non-specific endonuclease; High confidence in function and specificity. | 0.715 |
| nucA | HELO_3530 | HELO_3529 | HELO_3530 | DNA/RNA non-specific endonuclease; High confidence in function and specificity. | Transcriptional regulator, AsnC family; Uncharacterized HTH-type transcriptional regulator PH1519 - Pyrococcus horikoshii, Specificity unclear. | 0.803 |
| nucA | HELO_3532 | HELO_3529 | HELO_3532 | DNA/RNA non-specific endonuclease; High confidence in function and specificity. | K09786 hypothetical protein; UPF0229 protein Csal_0882 - Chromohalobacter salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB 13768),InterPro: Protein of unknown function DUF444, High confidence in function and specificity; Belongs to the UPF0229 family. | 0.408 |
| nucA | HELO_3630 | HELO_3529 | HELO_3630 | DNA/RNA non-specific endonuclease; High confidence in function and specificity. | Epimerase; High confidence in function and specificity. | 0.666 |
| nucA | HELO_3931 | HELO_3529 | HELO_3931 | DNA/RNA non-specific endonuclease; High confidence in function and specificity. | Beta-lactamase-like; Ribonuclease Z - Bacillus cereus (strain ATCC 10987),InterPro: Beta-lactamase-like, High confidence in function and specificity. | 0.886 |
| nucA | fdsB | HELO_3529 | HELO_1898 | DNA/RNA non-specific endonuclease; High confidence in function and specificity. | NADH dehydrogenase (quinone); NADH-quinone oxidoreductase subunit F - Rickettsia bellii (strain OSU 85-389),InterPro: Respiratory-chain NADH dehydrogenase 51 kDa subunit, High confidence in function and specificity. | 0.715 |
| nucA | polA | HELO_3529 | HELO_4002 | DNA/RNA non-specific endonuclease; High confidence in function and specificity. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.531 |
| nucA | recJ | HELO_3529 | HELO_3855 | DNA/RNA non-specific endonuclease; High confidence in function and specificity. | Single-stranded-DNA-specific exonuclease recJ -Escherichia coli (strain K12),InterPro: Bacterial RecJ exonuclease, High confidence in function and specificity. | 0.442 |
| nucA | ycgB | HELO_3529 | HELO_3531 | DNA/RNA non-specific endonuclease; High confidence in function and specificity. | Uncharacterized protein ycgB - Escherichia coli (strain K12),InterPro: SpoVR, High confidence in function and specificity. | 0.434 |
| polA | nucA | HELO_4002 | HELO_3529 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | DNA/RNA non-specific endonuclease; High confidence in function and specificity. | 0.531 |