| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| HELO_3530 | HELO_3532 | HELO_3530 | HELO_3532 | Transcriptional regulator, AsnC family; Uncharacterized HTH-type transcriptional regulator PH1519 - Pyrococcus horikoshii, Specificity unclear. | K09786 hypothetical protein; UPF0229 protein Csal_0882 - Chromohalobacter salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB 13768),InterPro: Protein of unknown function DUF444, High confidence in function and specificity; Belongs to the UPF0229 family. | 0.505 |
| HELO_3530 | gltB | HELO_3530 | HELO_3753 | Transcriptional regulator, AsnC family; Uncharacterized HTH-type transcriptional regulator PH1519 - Pyrococcus horikoshii, Specificity unclear. | Glutamate synthase (NADPH), large subunit; Catalyzes the conversion of L-glutamine and 2-oxoglutarate into two molecules of L-glutamate. | 0.475 |
| HELO_3530 | nucA | HELO_3530 | HELO_3529 | Transcriptional regulator, AsnC family; Uncharacterized HTH-type transcriptional regulator PH1519 - Pyrococcus horikoshii, Specificity unclear. | DNA/RNA non-specific endonuclease; High confidence in function and specificity. | 0.803 |
| HELO_3530 | putA | HELO_3530 | HELO_1802 | Transcriptional regulator, AsnC family; Uncharacterized HTH-type transcriptional regulator PH1519 - Pyrococcus horikoshii, Specificity unclear. | Bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.468 |
| HELO_3530 | ycgB | HELO_3530 | HELO_3531 | Transcriptional regulator, AsnC family; Uncharacterized HTH-type transcriptional regulator PH1519 - Pyrococcus horikoshii, Specificity unclear. | Uncharacterized protein ycgB - Escherichia coli (strain K12),InterPro: SpoVR, High confidence in function and specificity. | 0.549 |
| HELO_3532 | HELO_3530 | HELO_3532 | HELO_3530 | K09786 hypothetical protein; UPF0229 protein Csal_0882 - Chromohalobacter salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB 13768),InterPro: Protein of unknown function DUF444, High confidence in function and specificity; Belongs to the UPF0229 family. | Transcriptional regulator, AsnC family; Uncharacterized HTH-type transcriptional regulator PH1519 - Pyrococcus horikoshii, Specificity unclear. | 0.505 |
| HELO_3532 | nucA | HELO_3532 | HELO_3529 | K09786 hypothetical protein; UPF0229 protein Csal_0882 - Chromohalobacter salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB 13768),InterPro: Protein of unknown function DUF444, High confidence in function and specificity; Belongs to the UPF0229 family. | DNA/RNA non-specific endonuclease; High confidence in function and specificity. | 0.408 |
| HELO_3532 | ycgB | HELO_3532 | HELO_3531 | K09786 hypothetical protein; UPF0229 protein Csal_0882 - Chromohalobacter salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB 13768),InterPro: Protein of unknown function DUF444, High confidence in function and specificity; Belongs to the UPF0229 family. | Uncharacterized protein ycgB - Escherichia coli (strain K12),InterPro: SpoVR, High confidence in function and specificity. | 0.996 |
| gltB | HELO_3530 | HELO_3753 | HELO_3530 | Glutamate synthase (NADPH), large subunit; Catalyzes the conversion of L-glutamine and 2-oxoglutarate into two molecules of L-glutamate. | Transcriptional regulator, AsnC family; Uncharacterized HTH-type transcriptional regulator PH1519 - Pyrococcus horikoshii, Specificity unclear. | 0.475 |
| gltB | putA | HELO_3753 | HELO_1802 | Glutamate synthase (NADPH), large subunit; Catalyzes the conversion of L-glutamine and 2-oxoglutarate into two molecules of L-glutamate. | Bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.938 |
| nucA | HELO_3530 | HELO_3529 | HELO_3530 | DNA/RNA non-specific endonuclease; High confidence in function and specificity. | Transcriptional regulator, AsnC family; Uncharacterized HTH-type transcriptional regulator PH1519 - Pyrococcus horikoshii, Specificity unclear. | 0.803 |
| nucA | HELO_3532 | HELO_3529 | HELO_3532 | DNA/RNA non-specific endonuclease; High confidence in function and specificity. | K09786 hypothetical protein; UPF0229 protein Csal_0882 - Chromohalobacter salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB 13768),InterPro: Protein of unknown function DUF444, High confidence in function and specificity; Belongs to the UPF0229 family. | 0.408 |
| nucA | ycgB | HELO_3529 | HELO_3531 | DNA/RNA non-specific endonuclease; High confidence in function and specificity. | Uncharacterized protein ycgB - Escherichia coli (strain K12),InterPro: SpoVR, High confidence in function and specificity. | 0.434 |
| putA | HELO_3530 | HELO_1802 | HELO_3530 | Bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | Transcriptional regulator, AsnC family; Uncharacterized HTH-type transcriptional regulator PH1519 - Pyrococcus horikoshii, Specificity unclear. | 0.468 |
| putA | gltB | HELO_1802 | HELO_3753 | Bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | Glutamate synthase (NADPH), large subunit; Catalyzes the conversion of L-glutamine and 2-oxoglutarate into two molecules of L-glutamate. | 0.938 |
| ycgB | HELO_3530 | HELO_3531 | HELO_3530 | Uncharacterized protein ycgB - Escherichia coli (strain K12),InterPro: SpoVR, High confidence in function and specificity. | Transcriptional regulator, AsnC family; Uncharacterized HTH-type transcriptional regulator PH1519 - Pyrococcus horikoshii, Specificity unclear. | 0.549 |
| ycgB | HELO_3532 | HELO_3531 | HELO_3532 | Uncharacterized protein ycgB - Escherichia coli (strain K12),InterPro: SpoVR, High confidence in function and specificity. | K09786 hypothetical protein; UPF0229 protein Csal_0882 - Chromohalobacter salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB 13768),InterPro: Protein of unknown function DUF444, High confidence in function and specificity; Belongs to the UPF0229 family. | 0.996 |
| ycgB | nucA | HELO_3531 | HELO_3529 | Uncharacterized protein ycgB - Escherichia coli (strain K12),InterPro: SpoVR, High confidence in function and specificity. | DNA/RNA non-specific endonuclease; High confidence in function and specificity. | 0.434 |