STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnaQ-2DNA polymerase III polC-type - Bacillus halodurans,InterPro: Exonuclease, High confidence in function and specificity. (208 aa)    
Predicted Functional Partners:
HELO_3546
K07182 CBS domain-containing protein; cAMP-dependent protein kinase regulatory subunit -Glomerella lagenarium (Anthracnose fungus) (Colletotrichum lagenarium),InterPro: Putative nucleotidyltransferase DUF294, High confidence in function and specificity.
 
    0.976
dnaE
DNA polymerase III, alpha subunit; High confidence in function and specificity.
   
 0.972
dnaN
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 0.959
dnaX
DNA polymerase III subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
   
 0.954
holA
DNA polymerase III subunit delta; High confidence in function and specificity.
    
 0.930
HELO_3441
DNA polymerase III polC-type - Oceanobacillus iheyensis,InterPro: Exonuclease, Specificity unclear.
  
  
  0.929
holB
DNA polymerase III subunit delta - Yersinia pestis,InterPro: DNA polymerase III delta prime subunit,High confidence in function and specificity.
   
  0.920
holC
DNA polymerase III subunit chi; High confidence in function and specificity.
   
 0.917
HELO_2740
DNA polymerase III subunit epsilon-like protein -Rhodobacter capsulatus (Rhodopseudomonas capsulata),InterPro: DNA polymerase III epsilon subunit,Specificity unclear.
 
  
0.915
dnaQ
DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.
     
  0.900
Your Current Organism:
Halomonas elongata
NCBI taxonomy Id: 768066
Other names: H. elongata DSM 2581, Halomonas elongata ATCC 33173, Halomonas elongata DSM 2581, Halomonas elongata str. DSM 2581, Halomonas elongata strain DSM 2581
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