node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALU24911.1 | ALU25459.1 | AS202_01440 | AS202_04525 | Isocitrate dehydrogenase; NADP-specific, catalyzes the formation of 2-oxoglutarate from isocitrate or oxalosuccinate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the monomeric-type IDH family. | Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.800 |
ALU24911.1 | ALU26018.1 | AS202_01440 | AS202_07610 | Isocitrate dehydrogenase; NADP-specific, catalyzes the formation of 2-oxoglutarate from isocitrate or oxalosuccinate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the monomeric-type IDH family. | Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.803 |
ALU24911.1 | ALU26080.1 | AS202_01440 | AS202_07940 | Isocitrate dehydrogenase; NADP-specific, catalyzes the formation of 2-oxoglutarate from isocitrate or oxalosuccinate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the monomeric-type IDH family. | 2-oxoglutarate dehydrogenase subunit E1; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.917 |
ALU24911.1 | ALU27607.1 | AS202_01440 | AS202_16285 | Isocitrate dehydrogenase; NADP-specific, catalyzes the formation of 2-oxoglutarate from isocitrate or oxalosuccinate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the monomeric-type IDH family. | Aspartate aminotransferase; Catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.803 |
ALU24911.1 | gltA | AS202_01440 | AS202_02260 | Isocitrate dehydrogenase; NADP-specific, catalyzes the formation of 2-oxoglutarate from isocitrate or oxalosuccinate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the monomeric-type IDH family. | Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. | 0.599 |
ALU24911.1 | mdh | AS202_01440 | AS202_12340 | Isocitrate dehydrogenase; NADP-specific, catalyzes the formation of 2-oxoglutarate from isocitrate or oxalosuccinate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the monomeric-type IDH family. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.909 |
ALU25459.1 | ALU24911.1 | AS202_04525 | AS202_01440 | Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Isocitrate dehydrogenase; NADP-specific, catalyzes the formation of 2-oxoglutarate from isocitrate or oxalosuccinate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the monomeric-type IDH family. | 0.800 |
ALU25459.1 | ALU25460.1 | AS202_04525 | AS202_04530 | Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Potassium channel protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.637 |
ALU25459.1 | ALU26018.1 | AS202_04525 | AS202_07610 | Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.919 |
ALU25459.1 | ALU26080.1 | AS202_04525 | AS202_07940 | Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-oxoglutarate dehydrogenase subunit E1; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.808 |
ALU25459.1 | ALU26541.1 | AS202_04525 | AS202_10430 | Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pyridine nucleotide-disulfide oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.480 |
ALU25459.1 | ALU27607.1 | AS202_04525 | AS202_16285 | Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aspartate aminotransferase; Catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.919 |
ALU25459.1 | gltA | AS202_04525 | AS202_02260 | Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. | 0.803 |
ALU25459.1 | mdh | AS202_04525 | AS202_12340 | Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.829 |
ALU25459.1 | mqo | AS202_04525 | AS202_13275 | Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Malate:quinone oxidoreductase; Malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.800 |
ALU25459.1 | pckA | AS202_04525 | AS202_03685 | Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. | 0.812 |
ALU25460.1 | ALU25459.1 | AS202_04530 | AS202_04525 | Potassium channel protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.637 |
ALU26018.1 | ALU24911.1 | AS202_07610 | AS202_01440 | Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Isocitrate dehydrogenase; NADP-specific, catalyzes the formation of 2-oxoglutarate from isocitrate or oxalosuccinate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the monomeric-type IDH family. | 0.803 |
ALU26018.1 | ALU25459.1 | AS202_07610 | AS202_04525 | Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.919 |
ALU26018.1 | ALU26080.1 | AS202_07610 | AS202_07940 | Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-oxoglutarate dehydrogenase subunit E1; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.814 |