| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ALM95063.1 | guaA | RO02_10825 | RO02_12270 | ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | 0.415 |
| ALM95063.1 | infB | RO02_10825 | RO02_10830 | ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | 0.999 |
| ALM95063.1 | ispH | RO02_10825 | RO02_09245 | ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.753 |
| ALM95063.1 | nusA | RO02_10825 | RO02_10820 | ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transcription elongation factor NusA; Participates in both transcription termination and antitermination. | 0.997 |
| ALM95063.1 | rbfA | RO02_10825 | RO02_10835 | ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. | 0.815 |
| ALM95063.1 | rplM | RO02_10825 | RO02_06440 | ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.993 |
| ALM95063.1 | rpsO | RO02_10825 | RO02_11040 | ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. | 0.991 |
| ALM95063.1 | truB | RO02_10825 | RO02_01845 | ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.990 |
| guaA | ALM95063.1 | RO02_12270 | RO02_10825 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.415 |
| guaA | gyrB | RO02_12270 | RO02_10130 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | DNA topoisomerase IV subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.468 |
| guaA | infB | RO02_12270 | RO02_10830 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | 0.680 |
| guaA | ispH | RO02_12270 | RO02_09245 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.733 |
| guaA | nusA | RO02_12270 | RO02_10820 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | Transcription elongation factor NusA; Participates in both transcription termination and antitermination. | 0.566 |
| guaA | ribF | RO02_12270 | RO02_02405 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | Bifunctional riboflavin kinase/FMN adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribF family. | 0.463 |
| guaA | rplM | RO02_12270 | RO02_06440 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.851 |
| guaA | rpsO | RO02_12270 | RO02_11040 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | 30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. | 0.646 |
| guaA | truB | RO02_12270 | RO02_01845 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.914 |
| gyrB | guaA | RO02_10130 | RO02_12270 | DNA topoisomerase IV subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | 0.468 |
| gyrB | truB | RO02_10130 | RO02_01845 | DNA topoisomerase IV subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.820 |
| infB | ALM95063.1 | RO02_10830 | RO02_10825 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
