Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ALM94301.1DNA topoisomerase I; Derived by automated computational analysis using gene prediction method: Protein Homology. (804 aa)    
Predicted Functional Partners:
nifJ
Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.822
ALM95325.1
Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.822
ALM94300.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.757
recQ
ATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.726
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 0.564
ALM94302.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.563
recA
DNA recombination/repair protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
    
 0.552
ALM93286.1
Exonuclease SbcC; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.551
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.551
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.484
Your Current Organism:
Fusobacterium nucleatum polymorphum
NCBI taxonomy Id: 76857
Other names: ATCC 10953, CCUG 9126, DSM 20482, F. nucleatum subsp. polymorphum, Fusibacterium nucleatum subsp. polymorphum, Fusobacterium nucleatum subsp. polymorphum, Fusobacterium polymorphum, JCM 12990, NCTC 10562
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.