STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mglMethionine gamma-lyase; Catalyzes the alpha,gamma-elimination of L-methionine to produce methanethiol, 2-oxobutanoate and ammonia; methanethiol (methyl mercaptan) is considered to be one of the main causes of the oral malodor associated with periodontitis. Also displays homocysteine desulfhydrase activity, degrading homocysteine to produce hydrogen sulfide, 2-oxobutanoate and ammonia. L-cysteine and S-methyl-L-cysteine are poor substrates for the enzyme. (395 aa)    
Predicted Functional Partners:
ALM94506.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.930
cysK
Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.856
ALM95325.1
Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.846
ALM94638.1
Pyridine nucleotide-disulfide oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sulfur carrier protein TusA family.
  
 
 0.845
ALM93840.1
Ferredoxin--nitrite reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
  
 
 0.843
ALM93875.1
Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.840
metF
5,10-methylenetetrahydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methylenetetrahydrofolate reductase family.
  
 0.792
metG
methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
   
 
 0.789
nifJ
Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.774
ALM93663.1
Sulfurtransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.770
Your Current Organism:
Fusobacterium nucleatum polymorphum
NCBI taxonomy Id: 76857
Other names: ATCC 10953, CCUG 9126, DSM 20482, F. nucleatum subsp. polymorphum, Fusibacterium nucleatum subsp. polymorphum, Fusobacterium nucleatum subsp. polymorphum, Fusobacterium polymorphum, JCM 12990, NCTC 10562
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