Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nadA2Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (298 aa)    
Predicted Functional Partners:
nadB
L-aspartate oxidase; Catalyzes the formation of oxaloacetate from L-aspartate; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
nadC
Nicotinate-nucleotide pyrophosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family.
 
 
 0.999
ALF16780.1
DNA-binding transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.804
valS
valine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      0.679
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
    0.653
iscS
Cysteine desulfurase; Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.
  
  
 0.540
sulD
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
     
 0.519
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
  
  
 0.495
ALF17842.1
Phosphoribosylformylglycinamidine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.488
mnmG
tRNA uridine 5-carboxymethylaminomethyl modification protein; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.
       0.452
Your Current Organism:
Fusobacterium nucleatum animalis
NCBI taxonomy Id: 76859
Other names: ATCC 51191, CCUG 32879, CIP 104879, DSM 19679, F. nucleatum subsp. animalis, Fusibacterium nucleatum subsp. animalis, Fusobacterium animalis, Fusobacterium nucleatum subsp. animalis, JCM 11025, NCTC 12276
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