STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (170 aa)    
Predicted Functional Partners:
purB
Adenylosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
 0.952
purH
Phosphoribosylaminoimidazolecarboxamide formyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.949
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
  
 0.922
deoD
Purine nucleoside phosphorylase DeoD-type; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.914
ALF16999.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the multicopper oxidase YfiH/RL5 family.
    
  0.902
ALF16795.1
Adenine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.900
relA
Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
  
  
 0.762
tdcF
Reactive intermediate/imine deaminase; Has endoribonuclease activity on mRNA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.762
ALF17096.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.756
ALF17095.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.750
Your Current Organism:
Fusobacterium nucleatum animalis
NCBI taxonomy Id: 76859
Other names: ATCC 51191, CCUG 32879, CIP 104879, DSM 19679, F. nucleatum subsp. animalis, Fusibacterium nucleatum subsp. animalis, Fusobacterium animalis, Fusobacterium nucleatum subsp. animalis, JCM 11025, NCTC 12276
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