Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ALF17210.1poly(A) polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (442 aa)    
Predicted Functional Partners:
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
 
     0.791
folA2
Diadenosine tetraphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.754
trkA2
Portal protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.751
glmM
Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
      0.690
pnpA
Polynucleotide phosphorylase/polyadenylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
  
 
 0.645
ALF17206.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.573
polA
DNA polymerase I; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.547
ALF17205.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.535
sulD
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
  
    0.526
ALF17211.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.522
Your Current Organism:
Fusobacterium nucleatum animalis
NCBI taxonomy Id: 76859
Other names: ATCC 51191, CCUG 32879, CIP 104879, DSM 19679, F. nucleatum subsp. animalis, Fusibacterium nucleatum subsp. animalis, Fusobacterium animalis, Fusobacterium nucleatum subsp. animalis, JCM 11025, NCTC 12276
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