STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cas2CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (94 aa)    
Predicted Functional Partners:
cas1
Subtype I-B CRISPR-associated endonuclease Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
 
 0.999
cas4
CRISPR-associated protein Cas4; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
 0.995
ALF18767.1
CRISPR-associated protein Cas3; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.954
ALF18768.1
CRISPR-associated protein Cas5; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.925
ALF18770.1
CRISPR-associated protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.922
ALF18922.1
CRISPR-associated protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.920
ALF18769.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.901
ALF18907.1
DNA polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.671
ALF17784.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.419
Your Current Organism:
Fusobacterium nucleatum animalis
NCBI taxonomy Id: 76859
Other names: ATCC 51191, CCUG 32879, CIP 104879, DSM 19679, F. nucleatum subsp. animalis, Fusibacterium nucleatum subsp. animalis, Fusobacterium animalis, Fusobacterium nucleatum subsp. animalis, JCM 11025, NCTC 12276
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.