STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADR18113.1Short-chain dehydrogenase/reductase SDR; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002347: IPR002198; KEGG: hch:HCH_00126 short-chain alcohol dehydrogenase-like protein; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short-chain alcohol dehydrogenase-like protein; PFAM: short chain dehydrogenase. (260 aa)    
Predicted Functional Partners:
ADR19135.1
3-oxoacyl-(acyl-carrier-protein) synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
  
 0.958
ADR19132.1
COGs: COG0331 (acyl-carrier-protein) S-malonyltransferase; InterPro IPR014043: IPR004410; KEGG: ddf:DEFDS_0151 [acyl-carrier-protein] S-malonyltransferase; PFAM: Acyl transferase; SPTR: [acyl-carrier-protein] S-malonyltransferase; TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase domain; TIGRFAM: malonyl CoA-acyl carrier protein transacylase.
  
 0.957
fabZ
Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
  
 0.935
ADR18908.1
Enoyl-(acyl-carrier-protein) reductase (NADH); COGs: COG0623 Enoyl-(acyl-carrier-protein); InterPro IPR002347; KEGG: ddf:DEFDS_1807 enoyl-[acyl-carrier protein] reductase (NADH); SPTR: Enoyl-[acyl-carrier protein] reductase (NADH); PFAM: short chain dehydrogenase.
  
 
 0.929
fabH
3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
  
 
 0.925
ADR19133.1
3-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
  
 
0.922
ADR18114.1
2-dehydropantoate 2-reductase; COGs: COG1893 Ketopantoate reductase; InterPro IPR020476: IPR020084: IPR003710: IPR013332: IPR 013752: IPR000086; KEGG: ddf:DEFDS_2126 hypothetical protein; PFAM: Ketopantoate reductase ApbA/PanE domain protein; NUDIX hydrolase; SPTR: 2-dehydropantoate 2-reductase; TIGRFAM: 2-dehydropantoate 2-reductase; PFAM: Ketopantoate reductase PanE/ApbA; NUDIX domain; Ketopantoate reductase PanE/ApbA C terminal; TIGRFAM: 2-dehydropantoate 2-reductase.
     
 0.798
ADR18115.1
ATPase AAA-2 domain protein; COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterPro IPR001270: IPR018368: IPR004176: IPR003959: IPR 013093: IPR019489: IPR003593; KEGG: ddf:DEFDS_2127 ATP-dependent Clp protease ATP-binding subunit ClpC; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; Clp domain protein; Clp ATPase-like; SMART: AAA ATPase; SPTR: ATP-dependent Clp protease, ATP-binding subunit ClpC; PFAM: AAA domain (Cdc48 subfamily); Clp amino terminal domain; C-terminal, D2-small domain, of ClpB protein; ATPase family associated with various cel [...]
  
 
 0.767
ADR18119.1
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; COGs: COG1052 Lactate dehydrogenase and related dehydrogenase; InterPro IPR006139: IPR006140; KEGG: ddf:DEFDS_2131 D-isomer specific 2-hydroxyacid dehydrogenase catalytic component; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; SPTR: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic component; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain.
 
 
 0.639
ADR19917.1
PglZ domain protein; InterPro IPR014060: IPR013973; KEGG: esi:Exig_0316 alkaline phosphatase domain-containing protein; PFAM: PglZ domain protein; SPTR: PglZ domain protein; PFAM: PglZ domain; TIGRFAM: conserved hypothetical protein TIGR02687.
   
 
 0.638
Your Current Organism:
Calditerrivibrio nitroreducens
NCBI taxonomy Id: 768670
Other names: C. nitroreducens DSM 19672, Calditerrivibrio nitroreducens DSM 19672, Calditerrivibrio nitroreducens Yu37-1, Calditerrivibrio nitroreducens str. DSM 19672, Calditerrivibrio nitroreducens strain DSM 19672, Deferribacteraceae bacterium Yu37-1
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