STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADR18918.1Dihydroorotate oxidase B, electron transfer subunit; COGs: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase; InterPro IPR017927: IPR012165: IPR001433: IPR019480; KEGG: dap:Dacet_1422 oxidoreductase FAD/NAD(P)-binding domain protein; PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain; SPTR: Oxidoreductase FAD/NAD(P)-binding domain protein; PFAM: Oxidoreductase FAD-binding domain; Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B; Oxidoreductase [...] (264 aa)    
Predicted Functional Partners:
pyrD
Dihydroorotate oxidase B, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate.
 0.999
ADR18672.1
Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate.
 
 0.996
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 
 0.995
carB
COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterPro IPR006275: IPR011761: IPR005483: IPR005481: IPR 005479: IPR005480: IPR011607; KEGG: ddf:DEFDS_1217 carbamoylphosphate synthase large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; MGS domain protein; SPTR: Carbamoylphosphate synthase, large subunit; TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; MG [...]
  
 
 0.991
pyrC
Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
 
 
 0.989
ADR19774.1
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR000759: IPR013027; KEGG: ddf:DEFDS_1613 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase.
 
 
 0.986
pyrF
Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
  
  
 0.949
pyrB
COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; InterPro IPR002082: IPR006132: IPR006131: IPR006130; KEGG: ddf:DEFDS_0841 aspartate carbamoyltransferase catalytic subunit; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; PRIAM: Aspartate carbamoyltransferase; SPTR: Aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFA [...]
  
  
 0.944
carA
COGs: COG0505 Carbamoylphosphate synthase small subunit; InterPro IPR001317: IPR011702: IPR006220: IPR017926: IPR 006274: IPR002474: IPR000991; KEGG: ddf:DEFDS_1021 carbamoylphosphate synthase small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; SPTR: Carbamoylphosphate synthase, small subunit; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family.
  
  
 0.940
ADR19886.1
NADH:flavin oxidoreductase/NADH oxidase; COGs: COG1902 NADH:flavin oxidoreductase Old Yellow Enzyme family; InterPro IPR013027: IPR000103: IPR001155; KEGG: ddf:DEFDS_1694 NADH:flavin oxidoreductase/NADH oxidase; PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: NADH:flavin oxidoreductase/NADH oxidase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; NADH:flavin oxidoreductase / NADH oxidase family.
  
 
 0.873
Your Current Organism:
Calditerrivibrio nitroreducens
NCBI taxonomy Id: 768670
Other names: C. nitroreducens DSM 19672, Calditerrivibrio nitroreducens DSM 19672, Calditerrivibrio nitroreducens Yu37-1, Calditerrivibrio nitroreducens str. DSM 19672, Calditerrivibrio nitroreducens strain DSM 19672, Deferribacteraceae bacterium Yu37-1
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.