STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
ADR18935.1COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR000160: IPR001789; KEGG: azl:AZL_024270 two-component response regulator, modulated diguanylate cyclase; PFAM: GGDEF domain containing protein; response regulator receiver; SMART: GGDEF domain containing protein; response regulator receiver; SPTR: GGDEF:Response regulator receiver; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; Response regulator receiver domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. (304 aa)    
Predicted Functional Partners:
ADR18934.1
COGs: COG0642 Signal transduction histidine kinase; InterPro IPR000014: IPR001610: IPR003661: IPR003594: IPR 001789: IPR005467: IPR000700: IPR008207: IPR004358: IPR013655; KEGG: sbl:Sbal_3505 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; histidine kinase A domain protein; response regulator receiver; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein; SPTR: Multi-sensor hybrid histidine kinase; TIGR [...]
 
0.997
ADR18711.1
PAS/PAC sensor hybrid histidine kinase; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterPro IPR000014: IPR001610: IPR003594: IPR001789: IPR 013767: IPR004358: IPR005467: IPR000700; KEGG: cts:Ctha_0490 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; PAC repeat-containing protein; PAS domain containing protein; response regulator receiver; SPTR: PAS/PAC sensor hybrid histidine kinase; TIGRFAM: [...]
 
 0.982
ADR19455.1
COGs: COG0642 Signal transduction histidine kinase; InterPro IPR013767: IPR003661: IPR003594: IPR001789: IPR 008207: IPR005467: IPR000014: IPR004358; KEGG: chu:CHU_2895 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; response regulator receiver; SPTR: Sensory box histidine kinase/response regulator; TIGRFAM: PAS sensor protein [...]
 
0.982
ADR19202.1
KEGG: ddf:DEFDS_0653 hypothetical protein; SPTR: Putative uncharacterized protein.
  
 
 0.966
ADR19452.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); COGs: COG2200 FOG: EAL domain; InterPro IPR000215: IPR013767: IPR000160: IPR001633: IPR 000014: IPR000700; KEGG: eba:p1B362 sensory box protein; PFAM: EAL domain protein; GGDEF domain containing protein; PAS fold domain protein; SMART: EAL domain protein; GGDEF domain containing protein; PAS domain containing protein; SPTR: NMT1/THI5 like family; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain; GGDEF domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain.
 
 0.947
ADR18712.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); COGs: COG2200 FOG: EAL domain; InterPro IPR000014: IPR000160: IPR001633: IPR013767: IPR 000700; KEGG: ddf:DEFDS_1853 signal transduction sensor histidine kinase/response regulator; PFAM: EAL domain protein; PAS fold domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein; PAS domain containing protein; SPTR: Signal transduction sensor histidine kinase/response regulator; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: EAL domain; GGDEF domain; PAS fold; TIGRFAM: PAS [...]
 
 0.946
ADR18116.1
Metal dependent phosphohydrolase; COGs: COG2206 HD-GYP domain; InterPro IPR006674: IPR003607; KEGG: ddf:DEFDS_2128 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: Metal dependent phosphohydrolase; PFAM: Domain of unknown function (DUF3391); HD domain; TIGRFAM: uncharacterized domain HDIG.
 
   
 0.945
ADR18673.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterPro IPR000014: IPR000160: IPR001633: IPR013767; KEGG: nis:NIS_0136 hypothetical protein; PFAM: EAL domain protein; GGDEF domain containing protein; PAS fold domain protein; SMART: EAL domain protein; GGDEF domain containing protein; PAS domain containing protein; SPTR: Putative uncharacterized protein; TIGRFAM: diguanylate cyclase; PAS sensor protein; manually curated; PFAM: EAL domain; GGDEF domain; PAS fold; TIGRFAM: PAS [...]
 
 0.934
ADR19546.1
Response regulator receiver modulated metal dependent phosphohydrolase; COGs: COG2206 HD-GYP domain; InterPro IPR001789: IPR006674: IPR006675: IPR003607; KEGG: ddf:DEFDS_1712 hypothetical protein; PFAM: response regulator receiver; metal-dependent phosphohydrolase HD sub domain; SMART: response regulator receiver; metal-dependent phosphohydrolase HD region; SPTR: Putative uncharacterized protein; TIGRFAM: metal dependent phophohydrolase; PFAM: HD domain; Response regulator receiver domain; TIGRFAM: uncharacterized domain HDIG.
  
 0.934
ADR19196.1
COGs: COG0642 Signal transduction histidine kinase; InterPro IPR005467: IPR003660: IPR004358: IPR003661: IPR 003594; KEGG: ddf:DEFDS_0982 hypothetical protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: Putative uncharacterized protein; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
 
 0.933
Your Current Organism:
Calditerrivibrio nitroreducens
NCBI taxonomy Id: 768670
Other names: C. nitroreducens DSM 19672, Calditerrivibrio nitroreducens DSM 19672, Calditerrivibrio nitroreducens Yu37-1, Calditerrivibrio nitroreducens str. DSM 19672, Calditerrivibrio nitroreducens strain DSM 19672, Deferribacteraceae bacterium Yu37-1
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