STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADR19570.1Two component, sigma54 specific, transcriptional regulator, Fis family; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR002078: IPR001789: IPR002197: IPR003593: IPR 020441; KEGG: ddf:DEFDS_1092 two-component system response regulator PilR; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; helix-turn-helix Fis-type; SMART: response regulator receiver; AAA ATPase; SPTR: Two-component system response regulator PilR; PFAM: Response regulator receiver domain; Bacterial regulatory prot [...] (446 aa)    
Predicted Functional Partners:
ADR19552.1
COGs: COG3852 Signal transduction histidine kinase nitrogen specific; InterPro IPR003661: IPR003594: IPR005467; KEGG: ddf:DEFDS_1112 hypothetical protein; PFAM: histidine kinase A domain protein; ATP-binding region ATPase domain protein; SMART: histidine kinase A domain protein; ATP-binding region ATPase domain protein; SPTR: Putative uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
 
  0.981
ADR19338.1
COGs: COG1508 DNA-directed RNA polymerase specialized sigma subunit sigma54 homolog; InterPro IPR000394: IPR007046: IPR007634; KEGG: ddf:DEFDS_1044 DNA-directed RNA polymerase sigma 54 factor; PFAM: sigma-54 DNA-binding domain protein; sigma-54 factor core-binding region; sigma-54 factor; SPTR: DNA-directed RNA polymerase sigma 54 factor; TIGRFAM: RNA polymerase sigma-54 factor, RpoN; PFAM: Sigma-54 factor, Activator interacting domain (AID); Sigma-54 factor, core binding domain; Sigma-54, DNA binding domain; TIGRFAM: RNA polymerase sigma-54 factor.
 
  
 0.951
ADR19575.1
Diguanylate cyclase; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: dap:Dacet_0878 diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; SPTR: Diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
  
    0.782
greA
Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.
     
 0.781
ADR19573.1
Septum formation initiator; InterPro IPR007060; KEGG: ddf:DEFDS_1089 cell division protein FtsB; PFAM: Septum formation initiator; SPTR: Cell division protein FtsB; PFAM: Septum formation initiator.
  
    0.781
xseA
Exodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.
       0.780
ADR19574.1
KEGG: ddf:DEFDS_1088 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.780
ADR19576.1
Hypothetical protein; InterPro IPR003006; KEGG: ddf:DEFDS_1086 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.780
hfq-2
RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.
       0.780
ADR19567.1
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
    0.767
Your Current Organism:
Calditerrivibrio nitroreducens
NCBI taxonomy Id: 768670
Other names: C. nitroreducens DSM 19672, Calditerrivibrio nitroreducens DSM 19672, Calditerrivibrio nitroreducens Yu37-1, Calditerrivibrio nitroreducens str. DSM 19672, Calditerrivibrio nitroreducens strain DSM 19672, Deferribacteraceae bacterium Yu37-1
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