STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADR19812.1Aminotransferase class-III; COGs: COG0001 Glutamate-1-semialdehyde aminotransferase; InterPro IPR005814; KEGG: mar:MAE_38610 McyE protein; PFAM: aminotransferase class-III; SPTR: Amino acid adenylation; PFAM: Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (467 aa)    
Predicted Functional Partners:
ADR18095.1
Porphobilinogen synthase; COGs: COG0113 Delta-aminolevulinic acid dehydratase; InterPro IPR001731; KEGG: ddf:DEFDS_0812 porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; PRIAM: Porphobilinogen synthase; SPTR: Delta-aminolevulinic acid dehydratase; PFAM: Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
 
 0.984
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.974
ADR19450.1
Aminotransferase class-III; COGs: COG0001 Glutamate-1-semialdehyde aminotransferase; InterPro IPR005814; KEGG: dap:Dacet_2807 aminotransferase class-III; PFAM: aminotransferase class-III; SPTR: Aminotransferase class-III; PFAM: Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
  
 
0.925
hemL
COGs: COG0001 Glutamate-1-semialdehyde aminotransferase; InterPro IPR005814: IPR004639; KEGG: ddf:DEFDS_1739 glutamate-1-semialdehyde 2,1-aminomutase; PFAM: aminotransferase class-III; SPTR: Glutamate-1-semialdehyde 2,1-aminomutase; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: Aminotransferase class-III; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase.
  
  
 
0.924
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
  
 0.807
ADR19813.1
Protein of unknown function DUF77; COGs: COG0011 conserved hypothetical protein; InterPro IPR002767; KEGG: saf:SULAZ_1255 hypothetical protein; PFAM: protein of unknown function DUF77; SPTR: Putative uncharacterized protein; PFAM: Domain of unknown function DUF77; TIGRFAM: uncharacterized protein, MTH1187 family.
       0.732
ADR19811.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterPro IPR000014: IPR001638: IPR003661: IPR003594: IPR 001789: IPR005467: IPR004358: IPR013656: IPR013767; KEGG: ddf:DEFDS_1294 hypothetical protein; PFAM: ATP-binding region ATPase domain protein; extracellular solute-binding protein family 3; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; extracellular solute-binding protein family 3; PAS domain containing protein; histi [...]
  
    0.583
ADR19814.1
COGs: COG2378 transcriptional regulator protein; KEGG: pca:Pcar_0955 transcriptional regulator; SPTR: Putative uncharacterized protein.
       0.575
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
 0.539
ADR19620.1
Protein of unknown function DUF162; COGs: COG1139 conserved hypothetical protein containing a ferredoxin-like domain; InterPro IPR007087: IPR017900: IPR003741: IPR004017: IPR 017896; KEGG: ddf:DEFDS_1349 iron-sulfur cluster-binding protein; PFAM: protein of unknown function DUF162; protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: Iron-sulfur cluster-binding protein; PFAM: Cysteine-rich domain; Uncharacterised ACR, YkgG family COG1556; TIGRFAM: iron-sulfur cluster-binding protein.
   
    0.511
Your Current Organism:
Calditerrivibrio nitroreducens
NCBI taxonomy Id: 768670
Other names: C. nitroreducens DSM 19672, Calditerrivibrio nitroreducens DSM 19672, Calditerrivibrio nitroreducens Yu37-1, Calditerrivibrio nitroreducens str. DSM 19672, Calditerrivibrio nitroreducens strain DSM 19672, Deferribacteraceae bacterium Yu37-1
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