| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADR19887.1 | ADR19890.1 | Calni_1993 | Calni_1996 | Fmu (Sun) domain protein; COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR001678; KEGG: ddf:DEFDS_1153 hypothetical protein; PFAM: Fmu (Sun) domain protein; SPTR: Putative uncharacterized protein; PFAM: NOL1/NOP2/sun family; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR004392: IPR012202: IPR003495; KEGG: ddf:DEFDS_0182 hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; SPTR: Hydrogenase accessory protein HypB; TIGRFAM: hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB. | 0.737 |
| ADR19887.1 | ADR19892.1 | Calni_1993 | Calni_1998 | Fmu (Sun) domain protein; COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR001678; KEGG: ddf:DEFDS_1153 hypothetical protein; PFAM: Fmu (Sun) domain protein; SPTR: Putative uncharacterized protein; PFAM: NOL1/NOP2/sun family; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Site-2 protease; COGs: COG0750 membrane-associated Zn-dependent protease 1; InterPro IPR004387: IPR001478: IPR008915; KEGG: ddf:DEFDS_0124 membrane-associated zinc metalloprotease; PFAM: peptidase M50; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: Membrane-associated zinc metalloprotease; TIGRFAM: membrane-associated zinc metalloprotease; PFAM: Peptidase family M50; PDZ domain (Also known as DHR or GLGF); TIGRFAM: RIP metalloprotease RseP. | 0.800 |
| ADR19887.1 | ADR19894.1 | Calni_1993 | Calni_2000 | Fmu (Sun) domain protein; COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR001678; KEGG: ddf:DEFDS_1153 hypothetical protein; PFAM: Fmu (Sun) domain protein; SPTR: Putative uncharacterized protein; PFAM: NOL1/NOP2/sun family; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Phosphatidate cytidylyltransferase; COGs: COG0575 CDP-diglyceride synthetase; InterPro IPR000374; KEGG: ddf:DEFDS_0122 phosphatidate cytidylyltransferase; PFAM: phosphatidate cytidylyltransferase; SPTR: Phosphatidate cytidylyltransferase; PFAM: Cytidylyltransferase family; Belongs to the CDS family. | 0.702 |
| ADR19887.1 | ADR19895.1 | Calni_1993 | Calni_2001 | Fmu (Sun) domain protein; COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR001678; KEGG: ddf:DEFDS_1153 hypothetical protein; PFAM: Fmu (Sun) domain protein; SPTR: Putative uncharacterized protein; PFAM: NOL1/NOP2/sun family; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Undecaprenyl pyrophosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.787 |
| ADR19887.1 | ADR19898.1 | Calni_1993 | Calni_2004 | Fmu (Sun) domain protein; COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR001678; KEGG: ddf:DEFDS_1153 hypothetical protein; PFAM: Fmu (Sun) domain protein; SPTR: Putative uncharacterized protein; PFAM: NOL1/NOP2/sun family; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | KEGG: ddf:DEFDS_0118 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.697 |
| ADR19887.1 | ADR19899.1 | Calni_1993 | Calni_2005 | Fmu (Sun) domain protein; COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR001678; KEGG: ddf:DEFDS_1153 hypothetical protein; PFAM: Fmu (Sun) domain protein; SPTR: Putative uncharacterized protein; PFAM: NOL1/NOP2/sun family; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | COGs: COG0681 Signal peptidase I; InterPro IPR000223: IPR019757: IPR019758: IPR019759; KEGG: ddf:DEFDS_0117 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; PRIAM: Signal peptidase I; SPTR: Signal peptidase I; TIGRFAM: signal peptidase I; PFAM: Peptidase S24-like; TIGRFAM: signal peptidase I, bacterial type; Belongs to the peptidase S26 family. | 0.667 |
| ADR19887.1 | dxr | Calni_1993 | Calni_1999 | Fmu (Sun) domain protein; COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR001678; KEGG: ddf:DEFDS_1153 hypothetical protein; PFAM: Fmu (Sun) domain protein; SPTR: Putative uncharacterized protein; PFAM: NOL1/NOP2/sun family; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.702 |
| ADR19887.1 | frr | Calni_1993 | Calni_2002 | Fmu (Sun) domain protein; COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR001678; KEGG: ddf:DEFDS_1153 hypothetical protein; PFAM: Fmu (Sun) domain protein; SPTR: Putative uncharacterized protein; PFAM: NOL1/NOP2/sun family; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.701 |
| ADR19887.1 | hypA | Calni_1993 | Calni_1997 | Fmu (Sun) domain protein; COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR001678; KEGG: ddf:DEFDS_1153 hypothetical protein; PFAM: Fmu (Sun) domain protein; SPTR: Putative uncharacterized protein; PFAM: NOL1/NOP2/sun family; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | 0.737 |
| ADR19887.1 | pyrH | Calni_1993 | Calni_2003 | Fmu (Sun) domain protein; COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR001678; KEGG: ddf:DEFDS_1153 hypothetical protein; PFAM: Fmu (Sun) domain protein; SPTR: Putative uncharacterized protein; PFAM: NOL1/NOP2/sun family; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.738 |
| ADR19890.1 | ADR19887.1 | Calni_1996 | Calni_1993 | Hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR004392: IPR012202: IPR003495; KEGG: ddf:DEFDS_0182 hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; SPTR: Hydrogenase accessory protein HypB; TIGRFAM: hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB. | Fmu (Sun) domain protein; COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR001678; KEGG: ddf:DEFDS_1153 hypothetical protein; PFAM: Fmu (Sun) domain protein; SPTR: Putative uncharacterized protein; PFAM: NOL1/NOP2/sun family; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.737 |
| ADR19890.1 | ADR19892.1 | Calni_1996 | Calni_1998 | Hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR004392: IPR012202: IPR003495; KEGG: ddf:DEFDS_0182 hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; SPTR: Hydrogenase accessory protein HypB; TIGRFAM: hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB. | Site-2 protease; COGs: COG0750 membrane-associated Zn-dependent protease 1; InterPro IPR004387: IPR001478: IPR008915; KEGG: ddf:DEFDS_0124 membrane-associated zinc metalloprotease; PFAM: peptidase M50; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: Membrane-associated zinc metalloprotease; TIGRFAM: membrane-associated zinc metalloprotease; PFAM: Peptidase family M50; PDZ domain (Also known as DHR or GLGF); TIGRFAM: RIP metalloprotease RseP. | 0.778 |
| ADR19890.1 | ADR19894.1 | Calni_1996 | Calni_2000 | Hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR004392: IPR012202: IPR003495; KEGG: ddf:DEFDS_0182 hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; SPTR: Hydrogenase accessory protein HypB; TIGRFAM: hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB. | Phosphatidate cytidylyltransferase; COGs: COG0575 CDP-diglyceride synthetase; InterPro IPR000374; KEGG: ddf:DEFDS_0122 phosphatidate cytidylyltransferase; PFAM: phosphatidate cytidylyltransferase; SPTR: Phosphatidate cytidylyltransferase; PFAM: Cytidylyltransferase family; Belongs to the CDS family. | 0.732 |
| ADR19890.1 | ADR19895.1 | Calni_1996 | Calni_2001 | Hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR004392: IPR012202: IPR003495; KEGG: ddf:DEFDS_0182 hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; SPTR: Hydrogenase accessory protein HypB; TIGRFAM: hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB. | Undecaprenyl pyrophosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.742 |
| ADR19890.1 | ADR19898.1 | Calni_1996 | Calni_2004 | Hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR004392: IPR012202: IPR003495; KEGG: ddf:DEFDS_0182 hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; SPTR: Hydrogenase accessory protein HypB; TIGRFAM: hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB. | KEGG: ddf:DEFDS_0118 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.732 |
| ADR19890.1 | ADR19899.1 | Calni_1996 | Calni_2005 | Hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR004392: IPR012202: IPR003495; KEGG: ddf:DEFDS_0182 hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; SPTR: Hydrogenase accessory protein HypB; TIGRFAM: hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB. | COGs: COG0681 Signal peptidase I; InterPro IPR000223: IPR019757: IPR019758: IPR019759; KEGG: ddf:DEFDS_0117 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; PRIAM: Signal peptidase I; SPTR: Signal peptidase I; TIGRFAM: signal peptidase I; PFAM: Peptidase S24-like; TIGRFAM: signal peptidase I, bacterial type; Belongs to the peptidase S26 family. | 0.698 |
| ADR19890.1 | dxr | Calni_1996 | Calni_1999 | Hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR004392: IPR012202: IPR003495; KEGG: ddf:DEFDS_0182 hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; SPTR: Hydrogenase accessory protein HypB; TIGRFAM: hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.732 |
| ADR19890.1 | frr | Calni_1996 | Calni_2002 | Hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR004392: IPR012202: IPR003495; KEGG: ddf:DEFDS_0182 hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; SPTR: Hydrogenase accessory protein HypB; TIGRFAM: hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB. | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.732 |
| ADR19890.1 | hypA | Calni_1996 | Calni_1997 | Hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR004392: IPR012202: IPR003495; KEGG: ddf:DEFDS_0182 hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; SPTR: Hydrogenase accessory protein HypB; TIGRFAM: hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB. | Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | 0.979 |
| ADR19890.1 | pyrH | Calni_1996 | Calni_2003 | Hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR004392: IPR012202: IPR003495; KEGG: ddf:DEFDS_0182 hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; SPTR: Hydrogenase accessory protein HypB; TIGRFAM: hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.732 |