Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fixCDehydrogenase, FixC family. (316 aa)    
Predicted Functional Partners:
TTX_0001
Inosine/xanthosine triphosphatase.
  
    0.785
uspA
Nucleotide-binding protein, UspA family.
       0.682
fixX
Ferredoxin-like protein.
  
 
 0.666
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
  
 0.655
dsrA
Sulfite reductase, dissimilatory-type, beta subunit.
     
 0.639
dsrA-2
Sulfite reductase, dissimilatory-type, alpha subunit.
     
 0.639
dsrA-3
Sulfite reductase, dissimilatory-type, alpha subunit.
     
 0.639
dsrA-4
Sulfite reductase, dissimilatory-type, beta subunit.
     
 0.639
dsrA-5
Dissimilatory siroheme-sulfite reductase alpha subunit.
     
 0.639
TTX_1102
4-hydroxybutyryl-CoA dehydratase.
     
 0.623
Your Current Organism:
Thermoproteus tenax
NCBI taxonomy Id: 768679
Other names: T. tenax Kra 1, Thermoproteus tenax DSM 2078, Thermoproteus tenax JCM 9277, Thermoproteus tenax Kra 1, Thermoproteus tenax str. Kra 1, Thermoproteus tenax strain Kra 1
Server load: low (24%) [HD]