Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
mrpMrp protein, ATPase involved in chromosome partitioning. (244 aa)    
Predicted Functional Partners:
hypA
Hydrogenase nickel incorporation protein.
 
 
   0.976
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
   
 
 0.731
nikR
Transcriptional regulator, CopG/MetJ family, putative nickel responsive regulator.
       0.680
nuoC
Ferredoxin:quinone oxidoreductase, complex I, subunit C.
    
 0.646
nuoEF
Respiratory chain oxidoreductase nuoE and nuoF subunits.
    
 0.617
fqoI/nuoI
Ferredoxin:quinone oxidoreductase, complex I, subunit I.
  
 
 0.558
nuoI
NADH dehydrogenase I chain I.
  
 
 0.558
cbiM-2
Cobalt ABC transporter, permease protein (C-terminus).
  
    0.554
cbiM-1
Cobalt ABC transporter, permease protein (N-terminus).
  
    0.521
fqoD/nuoD
Ferredoxin:quinone oxidoreductase, complex I, subunit D; Belongs to the complex I 49 kDa subunit family.
    
 0.509
Your Current Organism:
Thermoproteus tenax
NCBI taxonomy Id: 768679
Other names: T. tenax Kra 1, Thermoproteus tenax DSM 2078, Thermoproteus tenax JCM 9277, Thermoproteus tenax Kra 1, Thermoproteus tenax str. Kra 1, Thermoproteus tenax strain Kra 1
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