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top6A protein (Thermoproteus tenax) - STRING interaction network
"top6A" - Type II DNA topoisomerase VI subunit A in Thermoproteus tenax
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
top6AType II DNA topoisomerase VI subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity (366 aa)    
Predicted Functional Partners:
TTX_0745
Type II DNA topoisomerase VI subunit B (120 aa)
 
  0.999
TTX_0744
Type II DNA topoisomerase VI subunit B (373 aa)
 
  0.998
TTX_1038
Hypothetical protein (409 aa)
   
  0.963
rad50
Purine NTPase (704 aa)
     
  0.955
sbcC
SMC1-family ATPase involved in DNA repair (794 aa)
     
  0.955
radA
DNA repair protein; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules (382 aa)
     
  0.946
TTX_1160
RadA-like protein (310 aa)
     
  0.946
mre11
Exonuclease (378 aa)
     
  0.884
TTX_1531
XPF endonuclease (216 aa)
 
 
  0.883
fen
Flap-structure endonuclease; Structure-specific nuclease with 5’-flap endonuclease and 5’-3’ exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5’-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5’-end of a downstream Okazaki fragment. Binds the unpaired 3’-DNA end and kinks the DNA to facilitate 5’ cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pa [...] (346 aa)
     
 
  0.774
Your Current Organism:
Thermoproteus tenax
NCBI taxonomy Id: 768679
Other names: T. tenax, T. tenax Kra 1, Thermoproteus tenax, Thermoproteus tenax DSM 2078, Thermoproteus tenax JCM 9277, Thermoproteus tenax Kra 1, Thermoproteus tenax str. Kra 1, Thermoproteus tenax strain Kra 1
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