Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
arsBArsenite transport protein. (426 aa)    
Predicted Functional Partners:
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
  
 0.863
arsR
Transcriptional regulator, ArsR-family.
  
  
 0.741
TTX_1722
Predicted pyridoxal phosphate-dependent enzyme; Belongs to the DegT/DnrJ/EryC1 family.
  
  
 0.703
tatC
Sec-independent protein translocase; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes.
     
 0.698
cdc48
Cell division cycle protein, AAA family.
     
 0.674
sufC
Cysteine desulfurase activator ATPase.
     
 0.671
rfbA
dTDP-glucose pyrophosphorylase (glucose-1-phosphate thymidylyltransferase).
  
  
 0.656
TTX_0976
Aminopeptidase.
     
 0.648
moxR
MoxR-like ATPase.
     
 0.639
cas4
CRISPR-associated protein Cas4 (RecB family exonuclease); CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). This may be a 5' to 3' ssDNA exonuclease (By similarity). Belongs to the CRISPR-associated exonuclease Cas4 family.
     
 0.630
Your Current Organism:
Thermoproteus tenax
NCBI taxonomy Id: 768679
Other names: T. tenax Kra 1, Thermoproteus tenax DSM 2078, Thermoproteus tenax JCM 9277, Thermoproteus tenax Kra 1, Thermoproteus tenax str. Kra 1, Thermoproteus tenax strain Kra 1
Server load: low (20%) [HD]