Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TTX_0809Saccharopine dehydrogenase family protein. (350 aa)    
Predicted Functional Partners:
hisS
Histidyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family.
     
 0.811
folE
GTP cyclohydrolase I.
   
   0.722
TTX_0810
Predicted DNA binding protein, contains leucin zipper domain.
       0.511
leuB
3-isopropylmalate dehydrogenase.
  
 
 0.484
nep1
Conserved hypothetical protein; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA.
       0.480
eiF5A
Translation initiation factor eIF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
       0.470
TTX_0926
Oxidoreductase (deaminating).
 
  
 0.452
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
 
  
 0.427
lysJ/argD
Acetyl-lysine/acetylornithine aminotransferase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily.
  
 
 0.419
lysC
Aspartate kinase.
  
  
 0.418
Your Current Organism:
Thermoproteus tenax
NCBI taxonomy Id: 768679
Other names: T. tenax Kra 1, Thermoproteus tenax DSM 2078, Thermoproteus tenax JCM 9277, Thermoproteus tenax Kra 1, Thermoproteus tenax str. Kra 1, Thermoproteus tenax strain Kra 1
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