Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
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Score
sucDsuccinyl-CoA synthetase, alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (293 aa)    
Predicted Functional Partners:
sucC
succinyl-CoA synthetase, beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 0.999
sdhC/frdC
Succinate dehydrogenase (succinate dehydrogenase/fumarate reductase), cytochrome b subunit.
  
 
 0.990
sdhB/frdB
Succinate dehydrogenase (succinate dehydrogenase/fumarate reductase), iron-sulfur subunit.
 
 0.988
frdB
Fumarate reductase (succinate dehydrogenase/fumarate reductase), iron-sulfur protein.
  
 0.986
sdhA/frdA
Succinate dehydrogenase (succinate dehydrogenase/fumarate reductase), flavoprotein subunit.
  
 0.980
frdA
Fumarate reductase (succinate dehydrogenase/fumarate reductase), flavoprotein subunit.
  
 0.980
sdhD/frdD
Succinate dehydrogenase (succinate dehydrogenase/fumarate reductase), subunit D.
  
 
 0.964
TTX_1101
Succinyl-CoA reductase.
  
 0.934
prpB
Carboxyphosphonoenolpyruvate phosphonomutase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
  
 0.933
oorB-2
2-oxoacid ferredoxin oxidoreductase beta subunit.
  
 
 0.928
Your Current Organism:
Thermoproteus tenax
NCBI taxonomy Id: 768679
Other names: T. tenax Kra 1, Thermoproteus tenax DSM 2078, Thermoproteus tenax JCM 9277, Thermoproteus tenax Kra 1, Thermoproteus tenax str. Kra 1, Thermoproteus tenax strain Kra 1
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