Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
Genes that are sometimes fused into single open reading frames.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
annotation not available (184 aa)
Predicted Functional Partners:
annotation not available (162 aa)
annotation not available (98 aa)
50S ribosomal protein L44e; Binds to the 23S rRNA (91 aa)
50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3’-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (339 aa)
50S ribosomal protein L7Ae; Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C’/D’ sRNAs (150 aa)
50S ribosomal protein L37Ae; Binds to the 23S rRNA (105 aa)
50S ribosomal protein L24e; Binds to the 23S rRNA (63 aa)
50S ribosomal protein L19e; Binds to the 23S rRNA (147 aa)
annotation not available (91 aa)
50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (203 aa)