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folD protein (Thermoproteus tenax) - STRING interaction network
"folD" - Methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase in Thermoproteus tenax
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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folDMethylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (317 aa)    
Predicted Functional Partners:
purN
Phosphoribosylglycinamide formyltransferase (277 aa)
 
 
  0.999
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (432 aa)
   
  0.995
mthfs
5-formyltetrahydrofolate cyclo-ligase (255 aa)
   
  0.990
purM
Phosphoribosylformylglycinamidine cyclo-ligase (307 aa)
   
   
  0.960
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP (510 aa)
   
   
  0.940
purD
Phosphoribosylamine--glycine ligase (485 aa)
   
 
  0.934
TTX_1790
Thymidylate synthase (117 aa)
       
  0.925
thyX
Thymidylate synthase; Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (244 aa)
       
  0.925
TTX_1969
Phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) (366 aa)
   
   
  0.925
TTX_0201
Hypothetical protein (377 aa)
         
    0.900
Your Current Organism:
Thermoproteus tenax
NCBI taxonomy Id: 768679
Other names: T. tenax, T. tenax Kra 1, Thermoproteus tenax, Thermoproteus tenax DSM 2078, Thermoproteus tenax JCM 9277, Thermoproteus tenax Kra 1, Thermoproteus tenax str. Kra 1, Thermoproteus tenax strain Kra 1
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