| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MSU_0003 | MSU_0005 | MSU_0003 | MSU_0005 | Putative membrane protein. | ABC transporter, ATP binding protein. | 0.631 |
| MSU_0003 | dnaA | MSU_0003 | MSU_0001 | Putative membrane protein. | dnaA chromosomal replication initiation protein. | 0.498 |
| MSU_0003 | dnaN | MSU_0003 | MSU_0002 | Putative membrane protein. | DNA polymerase III, beta subunit. | 0.789 |
| MSU_0003 | hrcA | MSU_0003 | MSU_0004 | Putative membrane protein. | Heat-inducible transcription repressor hrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.785 |
| MSU_0005 | MSU_0003 | MSU_0005 | MSU_0003 | ABC transporter, ATP binding protein. | Putative membrane protein. | 0.631 |
| MSU_0005 | dnaA | MSU_0005 | MSU_0001 | ABC transporter, ATP binding protein. | dnaA chromosomal replication initiation protein. | 0.406 |
| MSU_0005 | dnaN | MSU_0005 | MSU_0002 | ABC transporter, ATP binding protein. | DNA polymerase III, beta subunit. | 0.673 |
| MSU_0005 | hrcA | MSU_0005 | MSU_0004 | ABC transporter, ATP binding protein. | Heat-inducible transcription repressor hrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.658 |
| dnaA | MSU_0003 | MSU_0001 | MSU_0003 | dnaA chromosomal replication initiation protein. | Putative membrane protein. | 0.498 |
| dnaA | MSU_0005 | MSU_0001 | MSU_0005 | dnaA chromosomal replication initiation protein. | ABC transporter, ATP binding protein. | 0.406 |
| dnaA | dnaN | MSU_0001 | MSU_0002 | dnaA chromosomal replication initiation protein. | DNA polymerase III, beta subunit. | 0.517 |
| dnaA | hrcA | MSU_0001 | MSU_0004 | dnaA chromosomal replication initiation protein. | Heat-inducible transcription repressor hrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.541 |
| dnaA | rpoC | MSU_0001 | MSU_0700 | dnaA chromosomal replication initiation protein. | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.798 |
| dnaA | rpoD | MSU_0001 | MSU_0482 | dnaA chromosomal replication initiation protein. | RNA polymerase sigma factor rpoD; Belongs to the sigma-70 factor family. | 0.457 |
| dnaJ | dnaK | MSU_0473 | MSU_0707 | Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.996 |
| dnaJ | dnaN | MSU_0473 | MSU_0002 | Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | DNA polymerase III, beta subunit. | 0.487 |
| dnaJ | grpE | MSU_0473 | MSU_0474 | Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | 0.985 |
| dnaJ | hrcA | MSU_0473 | MSU_0004 | Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Heat-inducible transcription repressor hrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.674 |
| dnaJ | rpoC | MSU_0473 | MSU_0700 | Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.762 |
| dnaJ | rpoD | MSU_0473 | MSU_0482 | Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | RNA polymerase sigma factor rpoD; Belongs to the sigma-70 factor family. | 0.690 |
