Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AFQ45083.1PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. (382 aa)    
Predicted Functional Partners:
AFQ45431.1
EAL domain-containing protein; PFAM: EAL domain; Response regulator receiver domain; GGDEF domain.
 
  
 0.811
AFQ45099.1
Diguanylate phosphodiesterase; PFAM: Phosphotransferase system, EIIC; EAL domain; TIGRFAM: PTS system, lactose/cellobiose family IIC component.
 
  
 0.740
AFQ44417.1
PFAM: EAL domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
 
  
 0.723
AFQ45407.1
PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; Hpt domain.
  
 
 0.715
AFQ42717.1
HD-GYP domain-containing protein; PFAM: HD domain.
  
   0.631
AFQ45921.1
Putative domain HDIG-containing protein; PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG.
  
   0.613
AFQ46159.1
Putative domain HDIG-containing protein; PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG.
  
   0.608
AFQ44954.1
Putative domain HDIG-containing protein; PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG.
  
   0.606
AFQ43035.1
PFAM: EAL domain; GGDEF domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain.
 
 
0.599
AFQ45406.1
PFAM: HD domain; Response regulator receiver domain.
  
  
 0.589
Your Current Organism:
Desulfosporosinus meridiei
NCBI taxonomy Id: 768704
Other names: D. meridiei DSM 13257, Desulfosporosinus meridiei DSM 13257, Desulfosporosinus meridiei str. DSM 13257, Desulfosporosinus meridiei strain DSM 13257, Desulfosporosinus sp. S10
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