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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AET66901.1Metal-dependent hydrolase, beta-lactamase superfamily III; PFAM: Metallo-beta-lactamase superfamily. (267 aa)    
Predicted Functional Partners:
AET66760.1
tRNA nucleotidyltransferase/poly(A) polymerase; PFAM: DHHA1 domain; DHH family; CBS domain; Poly A polymerase head domain; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
  
  
 0.612
rpoC
DNA-directed RNA polymerase, beta'' subunit, predominant form; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.512
AET70791.1
BMC domain-containing protein; PFAM: BMC domain.
  
     0.425
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
    0.412
AET66900.1
Methylase involved in ubiquinone/menaquinone biosynthesis; PFAM: Methyltransferase domain.
       0.411
rph
Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
  
  
 0.410
AET69199.1
PFAM: Adenylate and Guanylate cyclase catalytic domain; GAF domain.
     
 0.408
AET66910.1
Di-/tricarboxylate transporter; PFAM: Sodium:sulfate symporter transmembrane region.
  
   
 0.403
trmB
tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
 
  
 0.403
Your Current Organism:
Desulfosporosinus orientis
NCBI taxonomy Id: 768706
Other names: D. orientis DSM 765, Desulfosporosinus orientis DSM 765, Desulfosporosinus orientis Singapore I, Desulfosporosinus orientis str. DSM 765, Desulfosporosinus orientis strain DSM 765
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