Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AET68710.1Deacetylase, histone deacetylase/acetoin utilization protein; PFAM: Histone deacetylase domain. (443 aa)    
Predicted Functional Partners:
AET68705.1
Stage V sporulation protein K; PFAM: ATPase family associated with various cellular activities (AAA); TIGRFAM: probable Rubsico expression protein CbbX; stage V sporulation protein K.
   
 0.970
AET68711.1
N-methylhydantoinase A/acetone carboxylase, beta subunit; PFAM: Hydantoinase/oxoprolinase; Hydantoinase/oxoprolinase N-terminal region.
 
   0.943
AET69446.1
DNA/RNA helicase, superfamily II, SNF2 family; PFAM: Helicase conserved C-terminal domain; SNF2 family N-terminal domain; Bacterial SNF2 helicase associated; SWIM zinc finger.
   
 0.895
mutS
DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
   
 
 0.882
mutL
DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
   
   0.871
AET69196.1
ABC-type multidrug transport system, ATPase and permease component; PFAM: ABC transporter; ABC transporter transmembrane region; Cyclic nucleotide-binding domain.
  
 0.857
AET67595.1
Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
  
 0.842
AET68858.1
Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
  
 0.842
AET70133.1
PFAM: Protein phosphatase 2C.
  
 
 0.840
atpD
ATP synthase, F1 beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family.
    
 0.840
Your Current Organism:
Desulfosporosinus orientis
NCBI taxonomy Id: 768706
Other names: D. orientis DSM 765, Desulfosporosinus orientis DSM 765, Desulfosporosinus orientis Singapore I, Desulfosporosinus orientis str. DSM 765, Desulfosporosinus orientis strain DSM 765
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