STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Malapachy_2790Sphingosine hydroxylase; Belongs to the sterol desaturase family. (396 aa)    
Predicted Functional Partners:
Malapachy_1725
Lcb5-sphingolipid long chain base kinase.
   
 0.960
Malapachy_0945
Longevity-assurance protein.
   
 0.955
Malapachy_4200
Ypc1-alkaline ceramidase.
     
 0.946
Malapachy_0056
Longevity assurance protein lag1 lac1.
   
 0.919
Malapachy_0044
Ceramide very long chain fatty acid hydroxylase; Ceramide hydroxylase involved in the hydroxylation of sphingolipid-associated very long chain fatty acids. Postulated to hydroxylate the very long chain fatty acid of dihydroceramides and phytoceramides at C-2; Belongs to the sterol desaturase family. SCS7 subfamily.
   
 
 0.917
Malapachy_2980
Sphingolipid delta(4)-desaturase; Delta(4)-fatty-acid desaturase which introduces a double bond at the 4-position in the long-chain base (LCB) of ceramides.
   
 
 0.886
Malapachy_2314
Oxidoreductase.
    
 0.867
Malapachy_0382
Uncharacterized protein.
   
 0.753
Malapachy_3708
Rcd1 protein involved in sexual development.
 
      0.729
Malapachy_3136
C-8 sterol isomerase.
   
 0.703
Your Current Organism:
Malassezia pachydermatis
NCBI taxonomy Id: 77020
Other names: M. pachydermatis, Pityrosporum pachydermatis
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