STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Malapachy_2015tRNA-splicing endonuclease subunit Sen2; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural [...] (438 aa)    
Predicted Functional Partners:
Malapachy_1812
Sti1-hsp90 cochaperone.
    
 0.806
Malapachy_2779
Pre-mrna-splicing factor slt11.
   
 0.785
Malapachy_3148
Uncharacterized protein.
    
 0.764
Malapachy_2450
Uncharacterized protein.
    
 0.744
Malapachy_2698
Heat shock protein 90.
    
 0.744
Malapachy_0274
Spt20 domain-containing protein.
    
 0.744
Malapachy_3634
60s ribosomal protein l9.
    
 0.741
Malapachy_1300
CS domain-containing protein.
   
 0.706
Malapachy_1194
Ssz1-regulator protein involved in pleiotropic drug resistance; Belongs to the heat shock protein 70 family.
    
 0.701
Malapachy_0144
Heat shock protein hss1; Belongs to the heat shock protein 70 family.
    
 0.701
Your Current Organism:
Malassezia pachydermatis
NCBI taxonomy Id: 77020
Other names: M. pachydermatis, Pityrosporum pachydermatis
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