Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Malapachy_1472NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme. (537 aa)    
Predicted Functional Partners:
Malapachy_0922
Nedd8 activating enzyme.
   
 0.994
Malapachy_1747
Nedd8-ubiquitin-like protein.
    
 0.974
Malapachy_0285
E2 ubiquitin-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.971
Malapachy_2073
Cullin-domain-containing protein; Belongs to the cullin family.
   
 0.843
Malapachy_2157
Scf complex member cullin 1; Belongs to the cullin family.
   
 0.843
Malapachy_2337
Component of the anaphase promoting complex; Belongs to the cullin family.
    
 0.806
Malapachy_0349
Cop9 signalosome complex subunit 5.
  
 0.799
Malapachy_2579
Small ubiquitin-related modifier.
   
 0.785
Malapachy_3642
Autophagy-related protein.
   
 0.777
Malapachy_1097
Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.
    
 0.755
Your Current Organism:
Malassezia pachydermatis
NCBI taxonomy Id: 77020
Other names: M. pachydermatis, Pityrosporum pachydermatis
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