Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Malapachy_0324Ept1-sn--diacylglycerol ethanolamine-and cholinephosphotransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (437 aa)    
Predicted Functional Partners:
PSD1
Phosphatidylserine decarboxylase proenzyme 1, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily.
   
 
 0.972
Malapachy_1410
Hsd1-er membrane protein.
     
 0.970
Malapachy_0761
Phospholipase.
     
 0.965
Malapachy_4008
Phosphatidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
   
 
 0.965
Malapachy_1356
LNS2 domain-containing protein.
   
 
 0.964
Malapachy_2217
Phosphatidylserine decarboxylase psd3.
     
 0.963
Malapachy_3461
Phosphatidyl-N-methylethanolamine N-methyltransferase; Catalyzes the second two steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylmonomethylethanolamine (PMME) to phosphatidyldimethylethanolamine (PDME) and of PDME to phosphatidylcholine (PC).
    
 0.961
Malapachy_2658
Endoplasmic reticulum protein; Belongs to the membrane-bound acyltransferase family.
     
 0.955
Malapachy_1035
Phosphatidylethanolamine N-methyltransferase; Catalyzes the first step of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME); Belongs to the class VI-like SAM-binding methyltransferase superfamily. CHO2 family.
   
 
 0.943
Malapachy_1139
Methyltransf_25 domain-containing protein.
     
 0.931
Your Current Organism:
Malassezia pachydermatis
NCBI taxonomy Id: 77020
Other names: M. pachydermatis, Pityrosporum pachydermatis
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