close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Malapachy_0733Aconitate hydratase. (1010 aa)    
Predicted Functional Partners:
Malapachy_4210
Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis.
   
 
0.966
Malapachy_1332
Homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 
 0.962
Malapachy_0772
Citrate synthase; Belongs to the citrate synthase family.
  
 0.949
Malapachy_3775
Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
  
 0.934
Malapachy_0798
Isocitrate dehydrogenase [NAD] subunit, mitochondrial.
  
 0.845
Malapachy_1285
Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.
  
 
0.838
Malapachy_1880
Isocitrate lyase.
  
 0.831
Malapachy_4063
Isocitrate lyase.
  
 0.816
Malapachy_0816
Mitochondrial nad-dependent isocitrate dehydrogenase subunit 1.
  
 0.804
Malapachy_1545
2-oxoglutarate dehydrogenase complex e1 component mitochondrial.
   
 
 0.728
Your Current Organism:
Malassezia pachydermatis
NCBI taxonomy Id: 77020
Other names: M. pachydermatis, Pityrosporum pachydermatis
Server load: low (36%) [HD]