Malapachy_1301 protein (Malassezia pachydermatis)

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Malapachy_1301

Pyrimidine 5-nucleotidase. (260 aa)

Predicted Functional Partners:

Malapachy_3138

0.914

Malapachy_4138

0.894

Malapachy_2212

0.879

Malapachy_3083

0.814

Malapachy_3298

0.763

Malapachy_2661

0.745

Malapachy_0406

0.742

Malapachy_1143

0.741

Malapachy_1811

0.725

Malapachy_1970

0.721

Your Current Organism:

Malassezia pachydermatis

NCBI taxonomy Id: 77020
Other names: M. pachydermatis, Pityrosporum pachydermatis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Malapachy_0406	Malapachy_1143	A0A0M8MLP3	A0A0M8MW80	Inosine-uridine preferring nucleoside hydrolase.	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.	0.822
Malapachy_0406	Malapachy_1301	A0A0M8MLP3	A0A0M8MLY5	Inosine-uridine preferring nucleoside hydrolase.	Pyrimidine 5-nucleotidase.	0.742
Malapachy_0406	Malapachy_1970	A0A0M8MLP3	A0A0M8MTX6	Inosine-uridine preferring nucleoside hydrolase.	Amp deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.	0.723
Malapachy_0406	Malapachy_4138	A0A0M8MLP3	A0A0M9VPG3	Inosine-uridine preferring nucleoside hydrolase.	Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.	0.636
Malapachy_1143	Malapachy_0406	A0A0M8MW80	A0A0M8MLP3	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.	Inosine-uridine preferring nucleoside hydrolase.	0.822
Malapachy_1143	Malapachy_1301	A0A0M8MW80	A0A0M8MLY5	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.	Pyrimidine 5-nucleotidase.	0.741
Malapachy_1143	Malapachy_1970	A0A0M8MW80	A0A0M8MTX6	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.	Amp deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.	0.897
Malapachy_1143	Malapachy_2212	A0A0M8MW80	A0A0M8MXG7	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.	Uncharacterized protein.	0.688
Malapachy_1143	Malapachy_3083	A0A0M8MW80	A0A0M9VR34	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	0.879
Malapachy_1143	Malapachy_3138	A0A0M8MW80	A0A0M8MPC1	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.	Nicotinamide-nucleotide adenylyltransferase; Belongs to the eukaryotic NMN adenylyltransferase family.	0.826
Malapachy_1143	Malapachy_4138	A0A0M8MW80	A0A0M9VPG3	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.	Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.	0.720
Malapachy_1301	Malapachy_0406	A0A0M8MLY5	A0A0M8MLP3	Pyrimidine 5-nucleotidase.	Inosine-uridine preferring nucleoside hydrolase.	0.742
Malapachy_1301	Malapachy_1143	A0A0M8MLY5	A0A0M8MW80	Pyrimidine 5-nucleotidase.	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.	0.741
Malapachy_1301	Malapachy_1811	A0A0M8MLY5	A0A0M8MT18	Pyrimidine 5-nucleotidase.	Nicotinate-nucleotide diphosphorylase.	0.725
Malapachy_1301	Malapachy_1970	A0A0M8MLY5	A0A0M8MTX6	Pyrimidine 5-nucleotidase.	Amp deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.	0.721
Malapachy_1301	Malapachy_2212	A0A0M8MLY5	A0A0M8MXG7	Pyrimidine 5-nucleotidase.	Uncharacterized protein.	0.879
Malapachy_1301	Malapachy_2661	A0A0M8MLY5	A0A0N0RSH7	Pyrimidine 5-nucleotidase.	Uncharacterized protein.	0.745
Malapachy_1301	Malapachy_3083	A0A0M8MLY5	A0A0M9VR34	Pyrimidine 5-nucleotidase.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	0.814
Malapachy_1301	Malapachy_3138	A0A0M8MLY5	A0A0M8MPC1	Pyrimidine 5-nucleotidase.	Nicotinamide-nucleotide adenylyltransferase; Belongs to the eukaryotic NMN adenylyltransferase family.	0.914
Malapachy_1301	Malapachy_3298	A0A0M8MLY5	A0A0M9VRC2	Pyrimidine 5-nucleotidase.	Pho81-cyclin-dependent kinase inhibitor.	0.763