STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Malapachy_1540Histone-fold-containing protein. (123 aa)    
Predicted Functional Partners:
Malapachy_3148
Uncharacterized protein.
    
 0.997
Malapachy_0811
Histone h2b; Belongs to the histone H2B family.
 
 
 0.985
Malapachy_1925
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
 
 
 0.979
Malapachy_0797
Histone H2A; Belongs to the histone H2A family.
 
 
 0.934
Malapachy_1344
Histone H2A; Belongs to the histone H2A family.
 
 
 0.923
Malapachy_0244
Snf5-domain-containing protein.
    
 0.914
Malapachy_3344
Set domain-containing protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.
 
 
 0.902
Malapachy_3244
Rum1 protein.
   
 0.899
Malapachy_0425
Chromosome condensation.
   
 0.893
Malapachy_0431
Histone-lysine n-methyltransferase setd1.
   
 0.889
Your Current Organism:
Malassezia pachydermatis
NCBI taxonomy Id: 77020
Other names: M. pachydermatis, Pityrosporum pachydermatis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.