close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Malapachy_2207Actin depolymerizing factor; Belongs to the actin-binding proteins ADF family. (147 aa)    
Predicted Functional Partners:
Malapachy_3024
Actin-like protein; Belongs to the actin family.
   
 0.986
Malapachy_2800
Adenylyl cyclase-associated protein; Belongs to the CAP family.
   
 0.945
Malapachy_2532
Heat shock protein 60; Belongs to the chaperonin (HSP60) family.
 
    
 0.905
Malapachy_0032
Uncharacterized protein.
   
 0.875
Malapachy_3689
Actin-related protein; Belongs to the actin family.
   
 0.863
Malapachy_1801
Cytoskeleton assembly control protein.
   
 0.863
Malapachy_2430
Wd40 repeat-like protein.
   
 
 0.856
Malapachy_1291
Actin binding protein; Belongs to the actin family.
   
 0.841
Malapachy_3448
Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
   
 0.839
Malapachy_3978
Act1-actin; Belongs to the actin family.
   
 0.815
Your Current Organism:
Malassezia pachydermatis
NCBI taxonomy Id: 77020
Other names: M. pachydermatis, Pityrosporum pachydermatis
Server load: low (22%) [HD]