Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Malapachy_2135Uncharacterized protein. (284 aa)    
Predicted Functional Partners:
Malapachy_1821
Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
      
 0.480
Malapachy_0697
Dna repair protein rad50.
      
 0.473
Malapachy_0632
Rds2-regulator of drug sensitivity.
      
 0.428
Malapachy_2107
Heat shock protein; Belongs to the heat shock protein 70 family.
    
 
 0.423
Malapachy_1899
Acetyl-synthetase-like protein.
    
 0.410
Malapachy_1820
Acetyl-synthetase-like protein.
    
 0.410
Malapachy_3845
Peroxisomal-coenzyme a synthetase.
    
 0.410
Malapachy_3565
4-coumarate-ligase.
    
 0.410
Malapachy_1454
Amp-dependent synthetase and ligase.
    
 0.410
Malapachy_2991
4-coumarate-ligase.
    
 0.410
Your Current Organism:
Malassezia pachydermatis
NCBI taxonomy Id: 77020
Other names: M. pachydermatis, Pityrosporum pachydermatis
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