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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Malapachy_4064Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. (126 aa)    
Predicted Functional Partners:
Malapachy_3024
Actin-like protein; Belongs to the actin family.
    
 0.975
Malapachy_1395
Cytokinesis protein bni1.
    
 0.900
Malapachy_1291
Actin binding protein; Belongs to the actin family.
   
 0.887
Malapachy_2612
Rho gtpase-activating protein.
    
 0.880
Malapachy_3689
Actin-related protein; Belongs to the actin family.
    
 0.880
Malapachy_1801
Cytoskeleton assembly control protein.
    
 0.880
Malapachy_3448
Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
   
 0.879
Malapachy_2800
Adenylyl cyclase-associated protein; Belongs to the CAP family.
   
 0.875
Malapachy_4240
Uncharacterized protein.
    
 0.865
Malapachy_1257
Uncharacterized protein.
    
 0.865
Your Current Organism:
Malassezia pachydermatis
NCBI taxonomy Id: 77020
Other names: M. pachydermatis, Pityrosporum pachydermatis
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