close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Malapachy_4016Dolichyl pyrophosphate (Dol-P-P) phosphatase. (452 aa)    
Predicted Functional Partners:
Malapachy_2183
Cytidine and deoxycytidylate deaminase zinc-binding region domain-containing protein.
   
 0.922
Malapachy_4226
Mss1p.
   
 
 0.904
Malapachy_2551
Trna pseudouridine synthase d.
  
 
 0.875
Malapachy_1817
Ribosomal protein l17; Belongs to the bacterial ribosomal protein bL17 family.
   
 
 0.833
NCS6
Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.
  
 0.830
Malapachy_2590
50s ribosomal protein l13; Belongs to the universal ribosomal protein uL13 family.
  
 
 0.806
Malapachy_0198
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
    
 0.794
Malapachy_3026
Rib7-htp reductase.
    
 0.794
Malapachy_2952
Adenosine kinase.
    
 0.794
Malapachy_0620
Mrpl9-mitochondrial ribosomal large subunit; Belongs to the universal ribosomal protein uL3 family.
   
 
 0.769
Your Current Organism:
Malassezia pachydermatis
NCBI taxonomy Id: 77020
Other names: M. pachydermatis, Pityrosporum pachydermatis
Server load: low (26%) [HD]