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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Malapachy_1030Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (894 aa)    
Predicted Functional Partners:
Malapachy_1769
Kinase; Belongs to the inositol phosphokinase (IPK) family.
    
 0.971
Malapachy_0836
Kinase; Belongs to the inositol phosphokinase (IPK) family.
    
 0.713
Malapachy_3298
Pho81-cyclin-dependent kinase inhibitor.
    
 
 0.600
Malapachy_1062
Letm1 RBD domain-containing protein.
 
      0.535
Malapachy_2469
Nucleosome assembly protein; Belongs to the nucleosome assembly protein (NAP) family.
    
   0.491
Malapachy_1829
Rrna pseudouridine synthase.
    
 
 0.471
Malapachy_2782
Transducin family protein wd-40 repeat family protein.
    
   0.436
Malapachy_1465
Inositol-1-monophosphatase.
 
    
 0.412
Your Current Organism:
Malassezia pachydermatis
NCBI taxonomy Id: 77020
Other names: M. pachydermatis, Pityrosporum pachydermatis
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