STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PIM1Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family. (1084 aa)    
Predicted Functional Partners:
Malapachy_2582
Bro1-domain-containing protein.
 
 
    0.752
Malapachy_1366
GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.
  
  
 0.742
Malapachy_0120
Conserved hypothetiocal protein.
    
 0.696
Malapachy_4034
Peroxisomal targeting signal-1 receptor.
   
 0.682
Malapachy_2442
Tpr-like protein.
   
 0.682
Malapachy_0012
Atp-dependent metallopeptidase hfl.
  
 
 0.619
Malapachy_3393
Peroxisomal protein involved in protein import-peroxin.
   
 0.615
Malapachy_1081
Peroxisomal membrane protein pex13.
   
 
 0.606
Malapachy_2221
P-loop containing nucleoside triphosphate hydrolase protein.
  
 
 0.602
Malapachy_0137
Heat shock protein hsp104; Belongs to the ClpA/ClpB family.
  
 
 0.602
Your Current Organism:
Malassezia pachydermatis
NCBI taxonomy Id: 77020
Other names: M. pachydermatis, Pityrosporum pachydermatis
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