STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Malapachy_0337Ubiquitin-protein ligase 1. (581 aa)    
Predicted Functional Partners:
Malapachy_0163
E3 ubiquitin-protein ligase huwe1.
 
  
  0.984
Malapachy_0685
Uncharacterized protein.
    
 0.848
Malapachy_2007
Ubiquitin domain containing protein.
   
 0.808
Malapachy_2668
Boi1-bem1 protein-binding protein.
   
 0.705
Malapachy_0582
Dsk2-ubiquitin-like protein.
   
 0.705
Malapachy_1747
Nedd8-ubiquitin-like protein.
   
 0.700
Malapachy_0736
Elongation factor 3.
   
   0.663
Malapachy_0151
Ubiquitin activating enzyme; Belongs to the ubiquitin-activating E1 family.
   
 0.604
Malapachy_4078
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]
    
 0.601
Malapachy_2009
Ufd4-ubiquitin-protein ligase.
   
 
0.594
Your Current Organism:
Malassezia pachydermatis
NCBI taxonomy Id: 77020
Other names: M. pachydermatis, Pityrosporum pachydermatis
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